Asian Mouse Mutagenesis Resource Association (AMMRA): mouse genetics and laboratory animal resources in the Asia Pacific
- Danielle
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The Asian Mouse Mutagenesis Useful resource Affiliation (AMMRA) is a non-profit group consisting of main useful resource and analysis establishments with rodent experience from inside the Asia Pacific area.
For greater than a decade, aiming to assist biomedical analysis and stimulate worldwide collaboration, AMMRA has all the time been a pleasant and passionate ally of Asian and Australian member establishments dedicated to sharing information, exchanging sources, and selling biomedical analysis. AMMRA can be missioned to world connection by working carefully with the consortiums such because the Worldwide Mouse Phenotyping Consortium and the Worldwide Mouse Pressure Useful resource.
This evaluate discusses the emergence of AMMRA and descriptions its many roles and duties in selling, helping, enriching analysis, and in the end enhancing world life science analysis high quality.
Genetic discount of mTOR extends lifespan in a mouse mannequin of Hutchinson-Gilford Progeria syndrome
Hutchinson-Gilford progeria syndrome (HGPS) is a uncommon accelerated ageing dysfunction most notably characterised by heart problems and untimely demise from myocardial infarction or stroke.
The vast majority of circumstances are attributable to a de novo single nucleotide mutation within the LMNA gene that prompts a cryptic splice donor web site, leading to manufacturing of a poisonous type of lamin A with a 50 amino acid inner deletion, termed progerin.
We beforehand reported the era of a transgenic murine mannequin of progeria carrying a human BAC harboring the frequent mutation, G608G, which within the single-copy state develops options of HGPS which might be restricted to the vascular system. Right here, we report the phenotype of mice bred to hold two copies of the BAC, which extra utterly recapitulate the phenotypic options of HGPS in pores and skin, adipose, skeletal, and vascular tissues.
We additional present that genetic discount of the mechanistic goal of rapamycin (mTOR) considerably extends lifespan in these mice, offering a rationale for pharmacologic inhibition of the mTOR pathway within the therapy of HGPS.
Mental Incapacity and Mind Creatine Deficit: Phenotyping of the Genetic Mouse Mannequin for GAMT Deficiency
Guanidinoacetate methyltransferase deficiency (GAMT-D) is one in every of three cerebral creatine (Cr) deficiency syndromes attributable to pathogenic variants within the GAMT gene (19p13.3). GAMT-D is characterised by the buildup of guanidinoacetic acid (GAA) and the depletion of Cr, which end in extreme world developmental delay (and mental incapacity), motion dysfunction, and epilepsy.
The GAMT knockout (KO) mouse mannequin presents biochemical alterations in bodily fluids, the mind, and muscle tissue, together with elevated GAA and decreased Cr and creatinine (Crn) ranges, that are just like these noticed in people.
On the behavioral stage, solely restricted and gentle alterations have been reported, with a big a part of analyzed behaviors being unaffected in GAMT KO as in contrast with wild-type mice. On the cerebral stage, decreased Cr and Crn and elevated GAA and different guanidine compound ranges have been noticed. However, the consequences of Cr deficiency and GAA accumulation on many neurochemical, morphological, and molecular processes haven’t but been explored.
On this evaluate, we summarize information concerning behavioral and cerebral GAMT KO phenotypes, and deal with uncharted behavioral alterations which might be comparable with the medical signs reported in GAMT-D sufferers, together with mental incapacity, poor speech, and autistic-like behaviors, in addition to unexplored Cr-induced cerebral alterations.
Techniques genetics evaluation of the LXS recombinant inbred mouse strains:Genetic and molecular insights into acute ethanol tolerance
We now have been utilizing the Inbred Lengthy- and Quick-Sleep mouse strains (ILS, ISS) and a recombinant inbred panel derived from them, the LXS, to research the genetic underpinnings of acute ethanol tolerance which is taken into account to be a threat issue for alcohol use issues (AUDs).
Right here, we’ve got used RNA-seq to look at the transcriptome of complete mind in 40 of the LXS strains eight hours after a saline or ethanol “pretreatment” as in earlier behavioral research. Roughly 1/Three of the 14,184 expressed genes had been considerably heritable and lots of had been distinctive to the pretreatment.
A number of thousand cis- and trans-eQTLs had been mapped; a portion of those additionally had been distinctive to pretreatment. Ethanol pretreatment triggered differential expression (DE) of 1,230 genes. Gene Ontology (GO) enrichment evaluation advised involvement in quite a few organic processes together with astrocyte differentiation, histone acetylation, mRNA splicing, and neuron projection growth.
Genetic correlation evaluation recognized a whole bunch of genes that had been correlated to the behaviors. GO evaluation indicated that these genes are concerned in gene expression, chromosome group, and protein transport, amongst others.
The expression profiles of the DE genes and genes correlated to AFT within the ethanol pretreatment group (AFT-Et) had been discovered to be just like profiles of HDAC inhibitors. Hdac1, a cis-regulated gene that’s situated on the peak of a beforehand mapped QTL for AFT-Et, was correlated to 437 genes, most of which had been additionally correlated to AFT-Et.
GO evaluation of those genes recognized a number of enriched organic course of phrases together with neuron-neuron synaptic transmission and potassium transport. In abstract, the outcomes recommend widespread genetic results on gene expression, together with results which might be pretreatment-specific.
Quite a lot of candidate genes and organic capabilities had been recognized that may very well be mediating the behavioral responses. Probably the most outstanding of those was Hdac1 which can be regulating genes related to glutamatergic signaling and potassium conductance.
Electroporation and genetic provide of Cas9 improve the era effectivity of CRISPR/Cas9 knock-in alleles in C57BL/6J mouse zygotes
CRISPR/Cas9 equipment delivered as ribonucleoprotein (RNP) to the zygote has grow to be a normal software for the event of genetically modified mouse fashions. In recent times, numerous experiences have demonstrated the efficient supply of CRISPR/Cas9 equipment through zygote electroporation as an alternative choice to the standard supply methodology of microinjection.
On this examine, we’ve got carried out side-by-side comparisons of the 2 RNP supply strategies throughout a number of gene loci and conclude that electroporation compares very favourably with typical pronuclear microinjection, and report an enchancment in mutagenesis effectivity when delivering CRISPR through electroporation for the era of straightforward knock-in alleles utilizing single-stranded oligodeoxynucleotide (ssODN) restore templates.
As well as, we present that the effectivity of knock-in mutagenesis could be additional elevated by electroporation of embryos derived from Cas9-expressing donor females. The maternal provide of Cas9 to the zygote avoids the need to ship the comparatively massive Cas9 protein, and excessive effectivity era of each indel and knock-in allele could be achieved by electroporation of small single-guide RNAs and ssODN restore templates alone.
Mouse LIF Protein |
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E40MOP2028 | EnoGene | 20ug | EUR 495 |
Recombinant Mouse LIF |
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Z200195 | ABM | 10 µg | EUR 85 |
Description: LIF is a multifunctional secreted glycoprotein that exists in both soluble and matrix-bound forms. It displays biologic activities ranging from the differentiation of myeloid leukemic cells into macrophage lineage to effects on bone metabolism, inflammation, neural development, embryogenesis, and the maintenance of implantation. It is now clear that LIF is related in both structure and mechanism of action to the interleukin IL-6 family of cytokines, which also includes IL-11, ciliary neurotrophic factor, oncostatin M, and cardiotrophin 1. The actions of these cytokines are mediated through specific cell-surface receptors that consist of a unique chain and the shared signal transducing subunit gp130. |
Recombinant Mouse LIF |
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Z200197 | ABM | 100 µg | EUR 385 |
Description: LIF is a multifunctional secreted glycoprotein that exists in both soluble and matrix-bound forms. It displays biologic activities ranging from the differentiation of myeloid leukemic cells into macrophage lineage to effects on bone metabolism, inflammation, neural development, embryogenesis, and the maintenance of implantation. It is now clear that LIF is related in both structure and mechanism of action to the interleukin IL-6 family of cytokines, which also includes IL-11, ciliary neurotrophic factor, oncostatin M, and cardiotrophin 1. The actions of these cytokines are mediated through specific cell-surface receptors that consist of a unique chain and the shared signal transducing subunit gp130. |
Recombinant Mouse LIF |
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Z200199 | ABM | 1.0 mg | EUR 1200 |
Description: LIF is a multifunctional secreted glycoprotein that exists in both soluble and matrix-bound forms. It displays biologic activities ranging from the differentiation of myeloid leukemic cells into macrophage lineage to effects on bone metabolism, inflammation, neural development, embryogenesis, and the maintenance of implantation (2). It is now clear that LIF is related in both structure and mechanism of action to the interleukin IL-6 family of cytokines, which also includes IL-11, ciliary neurotrophic factor, oncostatin M, and cardiotrophin 1 (2). The actions of these cytokines are mediated through specific cell-surface receptors that consist of a unique chain and the shared signal transducing subunit gp130. |
Recombinant Mouse LIF |
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Z200485 | ABM | 100 µg | EUR 1500 |
Description: LIF is a multifunctional secreted glycoprotein that exists in both soluble and matrix-bound forms. It displays biologic activities ranging from the differentiation of myeloid leukemic cells into macrophage lineage to effects on bone metabolism, inflammation, neural development, embryogenesis, and the maintenance of implantation (2). It is now clear that LIF is related in both structure and mechanism of action to the interleukin IL-6 family of cytokines, which also includes IL-11, ciliary neurotrophic factor, oncostatin M, and cardiotrophin 1 (2). The actions of these cytokines are mediated through specific cell-surface receptors that consist of a unique chain and the shared signal transducing subunit gp130. |
anti- LIF antibody |
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FNab09804 | FN Test | 100µg | EUR 658.5 |
Description: Antibody raised against LIF |
anti- LIF antibody |
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LSMab09804 | Lifescience Market | 100 ug | EUR 463.2 |
Mouse LIF ELISA Kit |
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EML0014 | Abclonal | 96Tests | EUR 625.2 |
Mouse LIF ELISA Kit |
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EK5250 | SAB | 96 tests | EUR 599 |
Mouse LIF ELISA Kit |
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E28L0650 | EnoGene | 96T | EUR 666.67 |
Mouse LIF shRNA Plasmid |
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20-abx971321 | Abbexa |
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Mouse LIF Recombinant Protein |
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M30-007 | ReliaTech | 10 µg | EUR 99.75 |
Description: Leukemia Inhibitory Factor also called LIF is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78% identity in its amino acid sequence. Human LIF is as active on human cells as is it is on mouse cells, though mouse LIF is about 1000 fold less active on human cells, than human LIF. Recombinant mouse LIF produced in E. coli is a single, non-glycosylated, polypeptide chain containing 180 amino acids and having a molecular mass of 19.86 kDa. |
Mouse LIF Recombinant Protein |
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M30-008 | ReliaTech | 50 µg | EUR 246.75 |
Description: Leukemia Inhibitory Factor also called LIF is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78% identity in its amino acid sequence. Human LIF is as active on human cells as is it is on mouse cells, though mouse LIF is about 1000 fold less active on human cells, than human LIF. Recombinant mouse LIF produced in E. coli is a single, non-glycosylated, polypeptide chain containing 180 amino acids and having a molecular mass of 19.86 kDa. |
Recombinant Mouse LIF Protein |
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R01400-1 | BosterBio | 100ug/vial | EUR 352.8 |
Anti-Human LIF Antibody |
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102-PA05 | ReliaTech | 200 µg | EUR 246.75 |
Description: Leukemia Inhibitory Factor also called LIF is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78% identity in its amino acid sequence. Human LIF is as active on human cells as is it is on mouse cells, though mouse LIF is about 1000 fold less active on human cells, than human LIF. |
Anti-Human LIF Antibody |
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102-PA05S | ReliaTech | 100 µg | EUR 126 |
Description: Leukemia Inhibitory Factor also called LIF is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78% identity in its amino acid sequence. Human LIF is as active on human cells as is it is on mouse cells, though mouse LIF is about 1000 fold less active on human cells, than human LIF. |
Anti-Human LIF Antibody |
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101-M553 | ReliaTech | 100 µg | EUR 399 |
Description: Based on its helical structure, LIF (Leukemia Inhibitory Factor) is considered a member of the Interleukin-6 family of cytokines. Functionally, it has been implicated in a many physiological processes including development, hematopoiesis, bone metabolism, and inflammation. Some cell types known to express LIF include activated T cells, monocytes, astrocytes, osteoblasts, keratinocytes, regenerating skeletal muscle, mast cells, and fibroblasts. |
LIF mouse monoclonal antibody, clone 4F7.2 |
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MO16101-100 | Origene Technologies GmbH | 100 µg | Ask for price |
LIF mouse monoclonal antibody, clone 2H2.2 |
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MO16102-100 | Origene Technologies GmbH | 100 µg | Ask for price |
Mouse LIF PicoKine ELISA Kit |
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EK0580 | BosterBio | 96 wells | EUR 510 |
Description: For quantitative detection of mouse LIF in cell culture supernates, serum and plasma (heparin, EDTA). |
Lif ORF Vector (Mouse) (pORF) |
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ORF049145 | ABM | 1.0 ug DNA | EUR 607.2 |
Lif ORF Vector (Mouse) (pORF) |
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ORF049146 | ABM | 1.0 ug DNA | EUR 607.2 |
LIF, Mouse Recombinant , 1MIU/ml |
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L4500-001 | GenDepot | 1ml | EUR 406.8 |
LIF, Mouse Recombinant , 1MIU/ml |
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L4500-005 | GenDepot | 5x1ml | EUR 1431.6 |
LIF ELISA Kit (Mouse) (OKBB00760) |
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OKBB00760 | Aviva Systems Biology | 96 Wells | EUR 606 |
Description: Description of target: Leukemia inhibitory factor, or LIF, is an interleukin 6 class cytokine that affects cell growth by inhibiting differentiation. When LIF levels drop, the cells differentiate. The LIF was mapped gene to 22q11-q12.2 by Southern analysis of a series of mouse/human somatic cell hybrids and by in situ hybridization to the chromosomes of 2 normal males and some individuals with chromosomal rearrangements. The gene maps between the Philadelphia translocation BCR1 and the breakpoint of the translocation in cell line GM2324 at 22q12.2. LIF derives its name from its ability to induce the terminal differentiation of myeloid leukemic cells, thus preventing their continued growth. Other properties attributed to the cytokine include: the growth promotion and cell differentiation of different types of target cells, influence on bone metabolism, cachexia, neural development, embryogenesis and inflammation.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: <10pg/ml |
LIF ELISA Kit (Mouse) (OKEH04045) |
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OKEH04045 | Aviva Systems Biology | 96 Wells | EUR 652.8 |
Description: Description of target: LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.039 ng/mL |
LIF, Mouse Recombinant , 10MIU/ml |
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L4501-001 | GenDepot | 1ml | EUR 1744.8 |
Nori® Mouse LIF ELISA Kit |
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GR117058 | Genorise Scientific | 96-well | EUR 461 |
Mouse LIF Recombinant Protein Lyophilized |
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IMSLIFRLY5UG | Innovative research | each | EUR 317 |
Description: Mouse LIF Recombinant Protein Lyophilized |
Human CellExp? LIF, mouse recombinant |
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7268-10 | Biovision | each | EUR 444 |
Leukemia Inhibitory Factor (LIF), mouse |
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PR16102 | Neuromics | 5 ug | EUR 522 |
Mouse LIF protein, C-His tag |
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PRP1126-100ug | Abbkine | 100 μg | EUR 379 |
Description: Mouse LIF protein, C-His tag, expressed in E. coli |
Mouse LIF protein, C-His tag |
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PRP1126-1mg | Abbkine | 1 mg | EUR 2509 |
Description: Mouse LIF protein, C-His tag, expressed in E. coli |
Mouse LIF protein, C-His tag |
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PRP1126-20ug | Abbkine | 20 μg | EUR 149 |
Description: Mouse LIF protein, C-His tag, expressed in E. coli |
Mouse LIF protein, C-His tag |
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PRP1126-5ug | Abbkine | 5 μg | EUR 59 |
Description: Mouse LIF protein, C-His tag, expressed in E. coli |
Lif (untagged) - Mouse leukemia inhibitory factor (Lif), transcript variant 1, (10ug) |
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MC208887 | Origene Technologies GmbH | 10 µg | Ask for price |
Lif (untagged) - Mouse leukemia inhibitory factor (Lif), transcript variant 2, (10ug) |
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MC208888 | Origene Technologies GmbH | 10 µg | Ask for price |
Recombinant Mouse Lif Protein, No Tag |
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E40MOP2217 | EnoGene | 20ug | EUR 495 |
Lif (GFP-tagged) - Mouse leukemia inhibitory factor (Lif) transcript variant 2, (10ug) |
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MG223901 | Origene Technologies GmbH | 10 µg | Ask for price |
Lif (GFP-tagged) - Mouse leukemia inhibitory factor (Lif) transcript variant 1, (10ug) |
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MG223120 | Origene Technologies GmbH | 10 µg | Ask for price |
Lif (Myc-DDK-tagged) - Mouse leukemia inhibitory factor (Lif), transcript variant 1 |
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MR223120 | Origene Technologies GmbH | 10 µg | Ask for price |
Lif (Myc-DDK-tagged) - Mouse leukemia inhibitory factor (Lif), transcript variant 2 |
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MR223901 | Origene Technologies GmbH | 10 µg | Ask for price |
OKBB00760-96W - LIF ELISA Kit (Mouse) |
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OKBB00760-96W | Aviva Systems Biology | 96wells | EUR 538 |
OKEH04045-96W - LIF ELISA Kit (Mouse) |
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OKEH04045-96W | Aviva Systems Biology | 96Wells | EUR 425 |
Leukemia Inhibitory Factor (LIF) Polyclonal Antibody (Mouse) |
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4-PAA085Mu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Leukemia Inhibitory Factor (LIF) |
Lif sgRNA CRISPR Lentivector set (Mouse) |
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K3872501 | ABM | 3 x 1.0 ug | EUR 406.8 |
LIF Antibody |
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6245-002mg | ProSci | 0.02 mg | EUR 206.18 |
Description: LIF Antibody: LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. LIF was initially recognized by its ability to induce terminal differentiation of myeloid leukemic cells. It is a member of the IL-6 cytokine superfamily and can be highly glycosylated. LIF signaling is transduced through the LIF-R/gp130 receptor complex, leading to the phosphorylation and activation of the JAK/STAT pathway. Recent evidence shows that LIF inhibits cardiomyogenesis in embryonic stem cells via STAT3 activation. |
LIF Antibody |
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6245-01mg | ProSci | 0.1 mg | EUR 523.7 |
Description: LIF Antibody: LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. LIF was initially recognized by its ability to induce terminal differentiation of myeloid leukemic cells. It is a member of the IL-6 cytokine superfamily and can be highly glycosylated. LIF signaling is transduced through the LIF-R/gp130 receptor complex, leading to the phosphorylation and activation of the JAK/STAT pathway. Recent evidence shows that LIF inhibits cardiomyogenesis in embryonic stem cells via STAT3 activation. |
LIF Antibody |
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25283-100ul | SAB | 100ul | EUR 468 |
LIF Antibody |
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1-CSB-PA012928ESR2HU | Cusabio |
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Description: A polyclonal antibody against LIF. Recognizes LIF from Human. This antibody is Unconjugated. Tested in the following application: ELISA |
LIF Antibody |
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E036950 | EnoGene | 100μg/100μl | EUR 255 |
Description: Available in various conjugation types. |
LIF Antibody |
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F49998-0.08ML | NSJ Bioreagents | 0.08 ml | EUR 140.25 |
Description: LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. |
LIF Antibody |
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F49998-0.4ML | NSJ Bioreagents | 0.4 ml | EUR 322.15 |
Description: LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. |
LIF Antibody |
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E38PA4058 | EnoGene | 100ul | EUR 225 |
Description: Available in various conjugation types. |
LIF Antibody |
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E315544 | EnoGene | 100ug/200ul | EUR 295 |
Description: Available in various conjugation types. |
LIF Antibody |
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E91288 | EnoGene | 100μg | EUR 255 |
Description: Available in various conjugation types. |
LIF Antibody |
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DF13730 | Affbiotech | 100ul | EUR 420 |
LIF Antibody |
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DF13730-100ul | Affinity Biosciences | 100ul | EUR 280 |
LIF Antibody |
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DF13730-200ul | Affinity Biosciences | 200ul | EUR 350 |
LIF Antibody |
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1-CSB-PA004761 | Cusabio |
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Description: A polyclonal antibody against LIF. Recognizes LIF from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/20000 |
LIF Antibody |
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36950 | SAB | 100ul | EUR 319 |
LIF Antibody |
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36950-100ul | SAB | 100ul | EUR 302.4 |
LIF Antibody |
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5216-100 | Biovision | each | EUR 379.2 |
LIF Antibody |
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5216-30T | Biovision | each | EUR 175.2 |
LIF antibody |
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70R-14100 | Fitzgerald | 100 ug | EUR 519 |
Description: Affinity purified Rabbit polyclonal LIF antibody |
LIF antibody |
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70R-6230 | Fitzgerald | 50 ug | EUR 467 |
Description: Rabbit polyclonal LIF antibody |
LIF antibody |
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70R-51295 | Fitzgerald | 100 ul | EUR 242 |
Description: Purified Polyclonal LIF antibody |
LIF antibody |
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70R-12299 | Fitzgerald | 100 ug | EUR 343 |
Description: Rabbit polyclonal LIF antibody |
LIF Antibody |
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1-CSB-PA198481 | Cusabio |
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Description: A polyclonal antibody against LIF. Recognizes LIF from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:10000, IHC:1:25-1:100 |
LIF Antibody |
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GWB-MT498C | GenWay Biotech | 50ug | Ask for price |
LIF Antibody |
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R30639 | NSJ Bioreagents | 100 ug | EUR 356.15 |
Description: LIF is a pleiotropic cytokine produced at the maternal-fetal interface which has been shown to play an essential role in implantation in mice. It is produced in high amounts by the human endometrium and the trophoblast itself, and its receptors are present on cytotrophoblast cells. LIF could thus play a role in modulating HLA-G production and immune tolerance at the maternal-fetal interface. The gene maps to 22q11-q12.2, between the Philadelphia translocation BCR gene and the breakpoint of the translocation in cell line GM2324 at 22q12.2. |
LIF Antibody |
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R31467 | NSJ Bioreagents | 100 ug | EUR 356.15 |
Description: LIF is a pleiotropic cytokine produced at the maternal-fetal interface which has been shown to play an essential role in implantation in mice. This gene is mapped to 22q11-q12.2, between the Philadelphia translocation BCR gene and the breakpoint of the translocation in cell line GM2324 at 22q12.2. LIF is produced in high amounts by the human endometrium and the trophoblast itself, and LIF receptors are present on cytotrophoblast cells. It could, thus, play a role in modulating HLA-G production and immune tolerance at the maternal-fetal interface. |
LIF Antibody |
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R36251-100UG | NSJ Bioreagents | 100 ug | EUR 339.15 |
Description: Additional name(s) for this target protein: Leukemia inhibitory factor |
LIF antibody |
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PAab09804 | Lifescience Market | 100 ug | EUR 463.2 |
LIF, Leukemia inhibitory factor, murine (mouse) |
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RC234-18 | Bio Basic | 5ug | EUR 125.26 |
Mouse Leukemia Inhibitory Factor (LIF) Protein |
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abx262959-1mg | Abbexa | 1 mg | EUR 3801.6 |
Mouse Leukemia Inhibitory Factor (LIF) Protein |
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abx262959-3x10g | Abbexa | 3x10 µg | EUR 393.6 |
Mouse Leukemia Inhibitory Factor (LIF) Protein |
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abx262959-3x2g | Abbexa | 3x2 µg | EUR 276 |
Mouse Leukemia Inhibitory Factor (LIF) Protein |
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20-abx067761 | Abbexa |
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Mouse LIF Protein, His Tag (MALS verified) |
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LIF-M5227 | ACROBIOSYSTEMS | 1mg | EUR 321 |
Description: Mouse LIF, His Tag (LIF-M5227) is expressed from human 293 cells (HEK293). It contains AA Ser 24 - Phe 203 (Accession # P09056-1). |
Mouse LIF Flow Cytometry Assay - Group 3 |
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MX85121 | Antigenix America | 96 Tests | EUR 270 |
Anti-Human LIF R alpha Antibody |
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101-M554 | ReliaTech | 100 µg | EUR 399 |
Description: The activities of the pleiotropic cytokine LIF are mediated through a high-affinity heterodimeric receptor complex consisting of two membrane glycoproteins: an alpha subunit (LIF R alpha, also known as LIF R beta and CD118) that binds LIF with low affinity and the 130 kDa (gp130) subunit that does not bind LIF by itself, but is required for high-affinity binding of LIF by the complex. |
Mouse LIF Protein, Tag Free (MALS verified) |
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LIF-M5219 | ACROBIOSYSTEMS | 20ug | EUR 2856.9 |
Description: Mouse LIF Protein, Tag Free (LIF-M5219) is expressed from human 293 cells (HEK293). It contains AA Ser 24 - Phe 203 (Accession # P09056-1). |
Recombinant Mouse Leukemia Inhibitory Factor/lIF |
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AP75318 | SAB | 1mg | EUR 3209 |
Recombinant Mouse Leukemia Inhibitory Factor/lIF |
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C690-10ug | Novoprotein | 10ug | EUR 175.2 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
Recombinant Mouse Leukemia Inhibitory Factor/lIF |
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C690-1mg | Novoprotein | 1mg | EUR 2739.6 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
Recombinant Mouse Leukemia Inhibitory Factor/lIF |
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C690-500ug | Novoprotein | 500ug | EUR 1935.6 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
Recombinant Mouse Leukemia Inhibitory Factor/lIF |
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C690-50ug | Novoprotein | 50ug | EUR 363.6 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
LIF |
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E8ER1912-32 | EnoGene | 100ul | EUR 275 |
Description: Available in various conjugation types. |
LIF |
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cyt-644 | ProSpec Tany | 5µg | EUR 60 |
Description: Recombinant Human Leukemia Inhibitory Factor |
anti-LIF |
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YF-PA12952 | Abfrontier | 50 ug | EUR 435.6 |
Description: Mouse polyclonal to LIF |
LIF Protein Vector (Mouse) (pPM-C-HA) |
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PV196580 | ABM | 500 ng | EUR 723.6 |
LIF Protein Vector (Mouse) (pPM-C-HA) |
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PV196584 | ABM | 500 ng | EUR 723.6 |
LIF Protein Vector (Mouse) (pPB-C-His) |
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PV196578 | ABM | 500 ng | EUR 723.6 |
LIF Protein Vector (Mouse) (pPB-N-His) |
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PV196579 | ABM | 500 ng | EUR 723.6 |
LIF Protein Vector (Mouse) (pPM-C-His) |
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PV196581 | ABM | 500 ng | EUR 723.6 |
LIF Protein Vector (Mouse) (pPB-C-His) |
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PV196582 | ABM | 500 ng | EUR 723.6 |
LIF Protein Vector (Mouse) (pPB-N-His) |
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PV196583 | ABM | 500 ng | EUR 723.6 |
LIF Protein Vector (Mouse) (pPM-C-His) |
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PV196585 | ABM | 500 ng | EUR 723.6 |
Leukemia Inhibitory Factor (LIF) Polyclonal Antibody (Mouse), PE |
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4-PAA085Mu01-PE | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Leukemia Inhibitory Factor (LIF). This antibody is labeled with PE. |
Leukemia Inhibitory Factor (LIF) Polyclonal Antibody (Mouse), APC |
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4-PAA085Mu01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Leukemia Inhibitory Factor (LIF). This antibody is labeled with APC. |
Leukemia Inhibitory Factor (LIF) Polyclonal Antibody (Mouse), Cy3 |
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4-PAA085Mu01-Cy3 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Leukemia Inhibitory Factor (LIF). This antibody is labeled with Cy3. |
Leukemia Inhibitory Factor (LIF) Polyclonal Antibody (Mouse), HRP |
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4-PAA085Mu01-HRP | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Leukemia Inhibitory Factor (LIF). This antibody is labeled with HRP. |
Mouse Lif/ Leukemia inhibitory factor ELISA Kit |
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E1656Mo | Sunlong | 1 Kit | EUR 543 |
Description: Differentiation-stimulating factor,D factor |
Mouse Lif(Leukemia inhibitory factor) ELISA Kit |
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EM0237 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 46.9pg/ml |
Leukemia Inhibitory Factor (LIF) Polyclonal Antibody (Mouse), FITC |
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4-PAA085Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Leukemia Inhibitory Factor (LIF). This antibody is labeled with FITC. |
Mouse LIF Protein (Ser 24-Phe 203) [His] |
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VAng-1946Lsx-20g | Creative Biolabs | 20 µg | EUR 588 |
Description: Mouse LIF protein, His tag, expressed in human 293 cells. (Uniprot ID: P09056) |
Mouse LIF Protein (Ser 24-Phe 203) [His] |
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VAng-1946Lsx-50g | Creative Biolabs | 50 µg | EUR 1050 |
Description: Mouse LIF protein, His tag, expressed in human 293 cells. (Uniprot ID: P09056) |
Recombinant Mouse LIF Protein, Untagged, E.coli-1mg |
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QP4235-1mg | EnQuireBio | 1mg | EUR 3189.6 |
Recombinant Mouse LIF Protein, Untagged, E.coli-5ug |
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QP4235-5ug | EnQuireBio | 5ug | EUR 163.2 |
Mouse LIF Recombinant Protein Tag Free Lyophilized |
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IMSLIFRTFLY50UG | Innovative research | each | EUR 681 |
Description: Mouse LIF Recombinant Protein Tag Free Lyophilized |
Recombinant Mouse LIF Protein, Untagged, E.coli-20ug |
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QP4235-20ug | EnQuireBio | 20ug | EUR 284.4 |
Recombinant Mouse LIF Protein, Untagged, E.coli-100ug |
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QP4235-100ug | EnQuireBio | 100ug | EUR 729.6 |
Recombinant Mouse LIF Protein, Untagged, E.coli-500ug |
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QP4235-500ug | EnQuireBio | 500ug | EUR 1992 |
Lif sgRNA CRISPR Lentivector (Mouse) (Target 1) |
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K3872502 | ABM | 1.0 ug DNA | EUR 184.8 |
Lif sgRNA CRISPR Lentivector (Mouse) (Target 2) |
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K3872503 | ABM | 1.0 ug DNA | EUR 184.8 |
Lif sgRNA CRISPR Lentivector (Mouse) (Target 3) |
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K3872504 | ABM | 1.0 ug DNA | EUR 184.8 |
Mouse Leukemia Inhibitory Factor (LIF) CLIA Kit |
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abx195395-96tests | Abbexa | 96 tests | EUR 990 |
Mouse LIF Recombinant Protein (Animal Free) Lyophilized |
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IMSLIFRAFLY5UG | Innovative research | each | EUR 333 |
Description: Mouse LIF Recombinant Protein (Animal Free) Lyophilized |
Mouse Leukemia Inhibitory Factor (LIF) ELISA Kit |
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DLR-LIF-Mu | DL Develop | 96T | EUR 432 |
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Mouse Leukemia Inhibitory Factor (LIF) ELISA Kit |
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DLR-LIF-Mu-48T | DL Develop | 48T | EUR 586.8 |
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Leukemia Inhibitory Factor (LIF) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Mouse Leukemia Inhibitory Factor (LIF) ELISA Kit |
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DLR-LIF-Mu-96T | DL Develop | 96T | EUR 762 |
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Leukemia Inhibitory Factor (LIF) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Mouse Leukemia inhibitory factor,LIF Elisa kit |
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EK731218 | AFG Bioscience LLC | 96 Wells | EUR 0.76 |
Mouse Leukemia inhibitory factor,LIF ELISA kit |
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EKC37279-48T | Biomatik Corporation | 48T | EUR 631.26 |
Mouse Leukemia inhibitory factor,LIF ELISA kit |
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EKC37279-5x96T | Biomatik Corporation | 5x96T | EUR 4283.55 |
Mouse Leukemia inhibitory factor,LIF ELISA kit |
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EKC37279-96T | Biomatik Corporation | 96T | EUR 901.8 |
Mouse Leukemia Inhibitory Factor (LIF) ELISA Kit |
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EKU11866-48T | Biomatik Corporation | 48T | EUR 514.08 |
Mouse Leukemia Inhibitory Factor (LIF) ELISA Kit |
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EKU11866-5x96T | Biomatik Corporation | 5x96T | EUR 3488.4 |
Mouse Leukemia Inhibitory Factor (LIF) ELISA Kit |
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EKU11866-96T | Biomatik Corporation | 96T | EUR 734.4 |
Mouse Leukemia Inhibitory Factor (LIF) ELISA Kit |
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EKN52977-48T | Biomatik Corporation | 48T | EUR 320.04 |
Mouse Leukemia Inhibitory Factor (LIF) ELISA Kit |
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EKN52977-5x96T | Biomatik Corporation | 5x96T | EUR 2171.7 |
Mouse Leukemia Inhibitory Factor (LIF) ELISA Kit |
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EKN52977-96T | Biomatik Corporation | 96T | EUR 457.2 |
Mouse Leukemia inhibitory factor(LIF)ELISA Kit |
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GA-E0658MS-48T | GenAsia Biotech | 48T | EUR 403.2 |
Mouse Leukemia inhibitory factor(LIF)ELISA Kit |
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GA-E0658MS-96T | GenAsia Biotech | 96T | EUR 640.8 |
Mouse Leukemia Inhibitory Factor (LIF) ELISA Kit |
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DL-LIF-Mu | DL Develop | 96T | EUR 412 |
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
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Moreover, electroporation, in comparison with microinjection, leads to the next price of embryo survival and growth. The tactic thus has the potential to cut back the variety of animals used within the manufacturing of genetically modified mouse fashions.
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