A 3D-QSAR model for the comprehensive bioenrichment and biodegradation effect of benzotriazole ultraviolet stabilisers and application of the model in molecular modification

A 3D-QSAR model for the comprehensive bioenrichment and biodegradation effect of benzotriazole ultraviolet stabilisers and application of the model in molecular modification

Ultraviolet (UV) absorber, a kind of sunshine stabiliser, has obtained appreciable consideration due to its excessive bioenrichment skill and low biodegradability. On this research, benzotriazole ultraviolet stabilisers (BUVSs) had been used because the analysis object, and the bioenrichment and biodegradation information of 13 varieties of BUVS molecules had been subjected to dimensionless processing by means…

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Physiological Functions of Mcl-1: Insights From Genetic Mouse Models

Physiological Functions of Mcl-1: Insights From Genetic Mouse Models

The flexibility to control the survival and demise of a cell is paramount all through the lifespan of a multicellular organism. Apoptosis, a foremost physiological type of programmed cell demise, is regulated by the Bcl-2 household proteins which are both pro-apoptotic or pro-survival. The in vivo features of distinct Bcl-2 members of the family are largely unmasked…

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