Identification of fibronectin 1 as a candidate genetic modifier in a Col4a1 mutant mouse model of Gould syndrome

Identification of fibronectin 1 as a candidate genetic modifier in a Col4a1 mutant mouse model of Gould syndrome

Collagen sort IV alpha 1 and alpha 2 (COL4A1 and COL4A2) are main parts of just about all basement membranes. COL4A1 and COL4A2 mutations trigger a multisystem dysfunction that may have an effect on any organ however usually entails the cerebral vasculature, eyes, kidneys and skeletal muscular tissues. In recent times, affected person advocacy and household help teams have united underneath the identify of Gould syndrome.
The manifestations of Gould syndrome are extremely variable, and animal research counsel that allelic heterogeneity and genetic context contribute to the scientific variability. We beforehand characterised a mouse mannequin of Gould syndrome attributable to a Col4a1 mutation by which the severities of ocular anterior phase dysgenesis (ASD), myopathy and intracerebral hemorrhage (ICH) have been depending on genetic background.
Right here, we carried out a genetic modifier display to offer perception into the mechanisms contributing to Gould syndrome pathogenesis and recognized a single locus [modifier of Gould syndrome 1 (MoGS1)] on Chromosome 1 that suppressed ASD.
A separate display confirmed that the identical locus ameliorated myopathy. Apparently, MoGS1 had no impact on ICH, suggesting that this phenotype might be mechanistically distinct. We refined the MoGS1 locus to a 4.three Mb interval containing 18 protein-coding genes, together with Fn1, which encodes the extracellular matrix part fibronectin 1. Molecular evaluation confirmed that the MoGS1 locus elevated Fn1 expression, elevating the chance that suppression is achieved by a compensatory extracellular mechanism.
Moreover, we discovered proof of elevated integrin-linked kinase ranges and focal adhesion kinase phosphorylation in Col4a1 mutant mice that’s partially restored by the MoGS1 locus, implicating the involvement of integrin signaling. Taken collectively, our outcomes counsel that tissue-specific mechanistic heterogeneity contributes to the variable expressivity of Gould syndrome and that perturbations in integrin signaling might play a job in ocular and muscular manifestations.

Dopaminergic Dysregulation in Syndromic Autism Spectrum Issues: Insights From Genetic Mouse Fashions

Autism spectrum dysfunction (ASD) is a neurodevelopmental dysfunction outlined by altered social interplay and communication, and repetitive, restricted, rigid behaviors. Roughly 1.5-2% of the overall inhabitants meet the diagnostic standards for ASD and a number of other mind areas together with the cortex, amygdala, cerebellum and basal ganglia have been implicated in ASD pathophysiology.
The midbrain dopamine system is a vital modulator of mobile and synaptic operate in a number of ASD-implicated mind areas through anatomically and functionally distinct dopaminergic projections. The dopamine speculation of ASD postulates that dysregulation of dopaminergic projection pathways might contribute to the behavioral manifestations of ASD, together with altered reward worth of social stimuli, adjustments in sensorimotor processing, and motor stereotypies.
On this overview, we look at the help for the concept that cell-autonomous adjustments in dopaminergic operate are a core part of ASD pathophysiology. We talk about the human literature supporting the involvement of altered dopamine signaling in ASD together with genetic, mind imaging and pharmacologic research.
We then concentrate on genetic mouse fashions of syndromic neurodevelopmental problems by which single gene mutations result in elevated threat for ASD. We spotlight research which have straight examined dopamine neuron quantity, morphology, physiology, or output in these fashions.
Total, we discover appreciable help for the concept that the dopamine system could also be dysregulated in syndromic ASDs; nevertheless, there doesn’t seem like a constant signature and a few fashions present elevated dopaminergic operate, whereas others have poor dopamine signaling.
We conclude that dopamine dysregulation is frequent in syndromic types of ASD however that the particular adjustments could also be distinctive to every genetic dysfunction and should not account for the complete spectrum of ASD-related manifestations.

genetic mannequin to check O-GlcNAc biking in immortalized mouse embryonic fibroblasts.

O-GlcNAcylation is an plentiful posttranslational protein modification by which the monosaccharide O-GlcNAc is added to Ser/Thr residues by O-GlcNAc transferase and eliminated by O-GlcNAcase. Analyses of O-GlcNAc-mediated signaling and metabolic phenomena are sophisticated by components together with unsatisfactory inhibitors and loss-of-function cell strains missing an identical genetic backgrounds.
On this work, we generated immortalized WT, Oga knockout, and Ogt floxed allele (Ogt floxed) mouse embryonic fibroblast (MEF) cell strains with related genetic backgrounds. These strains will facilitate experiments and function a platform to check O-GlcNAc biking in mammals. As a take a look at paradigm, we used the immortalized MEF strains to research how adjustments in O-GlcNAcylation affected pathological phosphorylation of the tau protein.
The exercise of glycogen synthase kinase 3β (GSK3β), a kinase that phosphorylates tau, decreases when expressed in Oga knockout MEFs in contrast with WT cells. Phosphorylation at Thr231 in recombinant, tauopathy-associated tau with a proline-to-leucine mutation at place 301 (P301L) was altered when expressed in MEFs with altered O-GlcNAc biking.
In mixture, our knowledge help that O-GlcNAc biking not directly impacts tau phosphorylation at Thr231, however tau phosphorylation was extremely variable, even in genetically secure, immortalized MEF cells. The variable nature of tau phosphorylation noticed right here helps the necessity to use cells akin to these generated right here with genetically outlined lesions and related backgrounds to check advanced organic processes.
Identification of fibronectin 1 as a candidate genetic modifier in a Col4a1 mutant mouse model of Gould syndrome

Built-in evaluation of human genetic affiliation research and mouse transcriptome suggests LBH and SHF genes as novel prone genes for amyloid-β accumulation in Alzheimer’s illness.

Alzheimer’s illness (AD) is a standard neurological illness that causes dementia in people. Though the experiences of related pathological genes have been rising, the molecular mechanism resulting in the buildup of amyloid-β (Aβ) in human mind continues to be not nicely understood.
To establish novel genes that trigger accumulation of Aβ in AD sufferers, we carried out an integrative evaluation by combining a human genetic affiliation research and transcriptome evaluation in mouse mind. First, we examined genome-wide gene expression ranges within the hippocampus, evaluating them to amyloid Aβ degree in mice with blended genetic backgrounds.
Subsequent, primarily based on a GWAS statistics obtained by a earlier research with human AD topics, we obtained gene-based statistics from the SNP-based statistics. We mixed p values from the 2 forms of evaluation throughout orthologous gene pairs in human and mouse into one p worth for every gene to judge AD susceptibility.
In consequence, we discovered 5 genes with vital p values on this built-in evaluation among the many 373 genes analyzed. We additionally examined the gene expression degree of those 5 genes within the hippocampus of unbiased human AD circumstances and management topics.

Semaphorin 6A (SEMA6A) Antibody

20-abx302320
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Mouse Semaphorin- 6A, Sema6a ELISA KIT

ELI-52928m 96 Tests
EUR 1038

Human Semaphorin 6A (SEMA6A)ELISA Kit

201-12-1088 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Semaphorin- 6A, SEMA6A ELISA KIT

ELI-52440h 96 Tests
EUR 988.8

Human Semaphorin 6A(SEMA6A)ELISA Kit

GA-E1104HM-48T 48T
EUR 346.8

Human Semaphorin 6A(SEMA6A)ELISA Kit

GA-E1104HM-96T 96T
EUR 559.2

Human Semaphorin 6A(SEMA6A)ELISA Kit

QY-E00788 96T
EUR 433.2

Mouse anti-SAH 6a

MA00306-50 50µg
EUR 417.6
Description: Mouse monoclonal antibody to S-Adenosylhomocysteine Clone 844-2

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 418.8

anti- Cytokeratin 6A antibody

FNab02215 100µg
EUR 658.5
Description: Antibody raised against Cytokeratin 6A

Anti-Rab 6A Antibody

A02911 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for Rab 6A Antibody (RAB6A) detection.tested for WB in Human, Mouse, Rat.

Anti-Cytokeratin 6A antibody

PAab02215 100 ug
EUR 463.2

Anti-Rab 6A antibody

STJ95302 200 µl
EUR 236.4
Description: Rabbit polyclonal to Rab 6A.

anti-Semaphorin 3D

YF-PA22776 50 ug
EUR 435.6
Description: Mouse polyclonal to Semaphorin 3D

anti-Semaphorin 3D

YF-PA22777 100 ug
EUR 483.6
Description: Rabbit polyclonal to Semaphorin 3D

anti-Semaphorin 3B

YF-PA25020 50 ul
EUR 400.8
Description: Mouse polyclonal to Semaphorin 3B

anti-Semaphorin 7a

YF-PA25109 50 ul
EUR 400.8
Description: Mouse polyclonal to Semaphorin 7a

anti-Semaphorin 3A

YF-PA25559 50 ul
EUR 400.8
Description: Mouse polyclonal to Semaphorin 3A

anti-Semaphorin 3B

YF-PA15485 100 ug
EUR 483.6
Description: Rabbit polyclonal to Semaphorin 3B

anti-Anti-Semaphorin 5A

YF-PA25252 50 ul
EUR 400.8
Description: Mouse polyclonal to Anti-Semaphorin 5A

CD6

6A-100T 100 test
EUR 418.8

anti- Cytokeratin 6A-specific antibody

FNab02216 100µg
EUR 658.5
Description: Antibody raised against Cytokeratin 6A-specific

Anti-Cytokeratin 6A-specific antibody

PAab02216 100 ug
EUR 463.2

Anti Mouse Semaphorin 3B Polyclonal Antibody

KR100
EUR 778.8
Description: The Anti Mouse Semaphorin 3B Polyclonal Antibody is available in Europe and for worldwide shipping via Gentaur.

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 336

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 336

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 336

Peptide 6A

H-6905.0005 5.0mg
EUR 356.4
Description: Sum Formula: C23H43N9O6; CAS# [73549-32-3]

Peptide 6A

H-6905.0025 25.0mg
EUR 1311.6
Description: Sum Formula: C23H43N9O6; CAS# [73549-32-3]

6a-Hydroxymaackiain

TB02758 5mg
EUR 1016.4

6a-Senecioyloxychaparrin

TBZ0849 unit Ask for price

6a-Hydroxyeurycomalactone

TBZ1429 unit Ask for price

Anti-Semaphorin 5A antibody

STJ70970 100 µg
EUR 430.8

Anti-Semaphorin 7a (3D3)

YF-MA16372 100 ug
EUR 435.6
Description: Mouse monoclonal to Semaphorin 7a

Anti-Semaphorin 7a (1G1)

YF-MA16373 100 ug
EUR 435.6
Description: Mouse monoclonal to Semaphorin 7a

Anti-Semaphorin 3A (5G9)

YF-MA17274 50 ug
EUR 435.6
Description: Mouse monoclonal to Semaphorin 3A

Anti-Semaphorin 4D (3B4)

YF-MA17342 100 ug
EUR 435.6
Description: Mouse monoclonal to Semaphorin 4D

Anti-Semaphorin 3B/SEMA3B Antibody

A06559-1 100ug/vial
EUR 352.8

Anti-SEMA4A/Semaphorin 4A Antibody

A06779-1 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for SEMA4A Antibody (SEMA4A) detection.tested for WB in Human, Mouse, Rat, Monkey.

Anti-Semaphorin 3E/SEMA3E Antibody

A06937-2 100ug/vial
EUR 352.8

Anti-SEMA4C/Semaphorin 4C Antibody

A08069 100ul
EUR 476.4
Description: Rabbit Polyclonal SEMA4C/Semaphorin 4C Antibody. Validated in WB and tested in Human.

Anti-Semaphorin 3A/SEMA3A Antibody

A01761-1 100ug/vial
EUR 352.8

Anti-Semaphorin 3c/SEMA3C Antibody

A06444-1 100ug/vial
EUR 352.8

Anti-Semaphorin 3A/SEMA3A Antibody

PB9353 100ug/vial
EUR 352.8

Anti-Semaphorin 3E (internal) antibody

STJ71055 100 µg
EUR 430.8

Cytokeratin 6a Antibody

DF7789 200ul
EUR 420

Estriol 6a antibody

20-1630 100 ul
EUR 1054.8
Description: Sheep polyclonal Estriol 6a antibody

Cytokeratin 6A Antibody

abx232215-100ug 100 ug
EUR 610.8

pFlag- CMV- 6a

PVT10705 2 ug
EUR 361.2

Mouse Keratin 6A (KRT6A) ELISA Kit

abx514580-96tests 96 tests
EUR 886.8

Mouse Semaphorin 7A ELISA kit

E03S0083-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 7A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Semaphorin 7A ELISA kit

E03S0083-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 7A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Semaphorin 7A ELISA kit

E03S0083-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 7A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Semaphorin 3 ELISA kit

E03S0084-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Semaphorin 3 ELISA kit

E03S0084-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Semaphorin 3 ELISA kit

E03S0084-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Semaphorin 4D ELISA kit

E03S0300-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 4D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Semaphorin 4D ELISA kit

E03S0300-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 4D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Semaphorin 4D ELISA kit

E03S0300-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 4D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Semaphorin 6D ELISA kit

E03S0464-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 6D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Semaphorin 6D ELISA kit

E03S0464-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 6D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Semaphorin 6D ELISA kit

E03S0464-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 6D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse semaphorin 3G ELISA kit

E03S0470-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Mouse semaphorin 3G in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse semaphorin 3G ELISA kit

E03S0470-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Mouse semaphorin 3G in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse semaphorin 3G ELISA kit

E03S0470-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Mouse semaphorin 3G in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Semaphorin 3A (SEMA3A) Protein

20-abx069022
  • EUR 811.20
  • EUR 326.40
  • EUR 2481.60
  • EUR 961.20
  • EUR 577.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Semaphorin 3E (SEMA3E) Protein

20-abx069024
  • EUR 794.40
  • EUR 326.40
  • EUR 2448.00
  • EUR 944.40
  • EUR 577.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Semaphorin 4B (SEMA4B) Protein

20-abx069029
  • EUR 910.80
  • EUR 360.00
  • EUR 2848.80
  • EUR 1078.80
  • EUR 644.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Semaphorin 5B (SEMA5B) Protein

20-abx069034
  • EUR 828.00
  • EUR 343.20
  • EUR 2548.80
  • EUR 978.00
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Semaphorin 7A (SEMA7A) Protein

20-abx167332
  • EUR 828.00
  • EUR 343.20
  • EUR 2548.80
  • EUR 978.00
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Semaphorin 4D (SEMA4D) Protein

20-abx167383
  • EUR 844.80
  • EUR 343.20
  • EUR 2598.00
  • EUR 994.80
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Semaphorin- 3G ELISA Kit

ELA-E7736m 96 Tests
EUR 1038

Semaphorin 5A

P41026 100 ug Blocking Peptide
EUR 286.8

Semaphorin 7A

MO15041 500 ug
EUR 615.6

Semaphorin 7A

GT15076 100 ug
EUR 646.8

Semaphorin 3C

GT15077 100 ug
EUR 631.2

Semaphorin 6B

GT15165 100 ug
EUR 631.2

Semaphorin 5A

GT41026 100 ug
EUR 568.8

Semaphorin 3B

RA25088 50 ul
EUR 568.8

Rab 6A Polyclonal Antibody

ES6964-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against Rab 6A from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

Rab 6A Polyclonal Antibody

ES6964-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against Rab 6A from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

Rab 6A Polyclonal Antibody

41378-100ul 100ul
EUR 302.4

Rab 6A Polyclonal Antibody

41378-50ul 50ul
EUR 224.4

Rab 6A Polyclonal Antibody

ABP55965-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Rab 6A from Human, Mouse, Rat. This Rab 6A antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Rab 6A at AA range: 90-170

Rab 6A Polyclonal Antibody

ABP55965-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Rab 6A from Human, Mouse, Rat. This Rab 6A antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Rab 6A at AA range: 90-170

Rab 6A Polyclonal Antibody

ABP55965-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Rab 6A from Human, Mouse, Rat. This Rab 6A antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Rab 6A at AA range: 90-170

Keratin 6A (KRT6A) Antibody

20-abx100825
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Keratin 6A (KRT6A) Antibody

20-abx100826
  • EUR 410.40
  • EUR 1028.40
  • EUR 526.80
  • EUR 184.80
  • EUR 309.60
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Keratin 6A (KRT6A) Antibody

20-abx100827
  • EUR 543.60
  • EUR 159.60
  • EUR 1562.40
  • EUR 744.00
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Keratin 6A (KRT6A) Antibody

20-abx109957
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Keratin 6A (KRT6A) Antibody

20-abx159587
  • EUR 326.40
  • EUR 276.00
  • 100 ug
  • 50 ug

Keratin 6A (KRT6A) Antibody

abx146382-100ug 100 ug
EUR 469.2

Keratin 6A (KRT6A) Antibody

20-abx113347
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Keratin 6A (KRT6A) Antibody

20-abx005878
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Keratin 6A (KRT6A) Antibody

20-abx002875
  • EUR 493.20
  • EUR 710.40
  • 100 ul
  • 200 ul

Keratin 6A (KRT6A) Antibody

abx029191-400ul 400 ul
EUR 627.6

Keratin 6A (KRT6A) Antibody

abx029191-80l 80 µl
EUR 343.2

PDE 6A Polyclonal Antibody

ABP-PAB-31042 50 ug Ask for price

Cytokeratin 6A-specific Antibody

abx232216-100ug 100 ug
EUR 610.8

Keratin 6A (KRT6A) Antibody

20-abx322514
  • EUR 526.80
  • EUR 393.60
  • 100 ul
  • 50 ul

Keratin 6A (KRT6A) Antibody

20-abx322515
  • EUR 526.80
  • EUR 393.60
  • 100 ul
  • 50 ul

Keratin 6A (KRT6A) Antibody

20-abx304308
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Keratin 6A (KRT6A) Antibody

20-abx214450
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Keratin 6A (KRT6A) Antibody

20-abx214451
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Recombinant Keratin 6A (KRT6A)

4-RPD234Hu01
  • EUR 528.58
  • EUR 265.20
  • EUR 1652.16
  • EUR 630.72
  • EUR 1141.44
  • EUR 429.60
  • EUR 3950.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Keratin 6A expressed in: E.coli

Recombinant Keratin 6A (KRT6A)

4-RPD234Ra01
  • EUR 571.58
  • EUR 276.00
  • EUR 1813.44
  • EUR 684.48
  • EUR 1248.96
  • EUR 458.40
  • EUR 4353.60
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Keratin 6A expressed in: E.coli

Anti Mouse Semaphorin 4A Monoclonal Antibody (Clone No. HIAT-2)

KO401
EUR 856.8
Description: The Anti Mouse Semaphorin 4A Monoclonal Antibody (Clone No. HIAT-2) is available in Europe and for worldwide shipping via Gentaur.

Anti Mouse Semaphorin 7A Monoclonal Antibody (Clone No. SKK-7)

KO402
EUR 856.8
Description: The Anti Mouse Semaphorin 7A Monoclonal Antibody (Clone No. SKK-7) is available in Europe and for worldwide shipping via Gentaur.

Mouse Semaphorin-3A(SEMA3A) ELISA kit

CSB-EL020980MO-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3A (SEMA3A) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Semaphorin-3A(SEMA3A) ELISA kit

1-CSB-EL020980MO
  • EUR 964.80
  • EUR 6118.80
  • EUR 3244.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3A(SEMA3A) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Semaphorin-3B(SEMA3B) ELISA kit

CSB-EL020981MO-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3B (SEMA3B) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Semaphorin-3B(SEMA3B) ELISA kit

1-CSB-EL020981MO
  • EUR 964.80
  • EUR 6118.80
  • EUR 3244.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3B(SEMA3B) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Semaphorin-3D(SEMA3D) ELISA kit

CSB-EL020983MO-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3D (SEMA3D) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Semaphorin-3D(SEMA3D) ELISA kit

1-CSB-EL020983MO
  • EUR 964.80
  • EUR 6118.80
  • EUR 3244.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3D(SEMA3D) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Semaphorin-3E(SEMA3E) ELISA kit

CSB-EL020984MO-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3E (SEMA3E) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Semaphorin-3E(SEMA3E) ELISA kit

1-CSB-EL020984MO
  • EUR 964.80
  • EUR 6118.80
  • EUR 3244.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3E(SEMA3E) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Semaphorin-3F(SEMA3F) ELISA kit

CSB-EL020985MO-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3F (SEMA3F) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Semaphorin-3F(SEMA3F) ELISA kit

1-CSB-EL020985MO
  • EUR 964.80
  • EUR 6118.80
  • EUR 3244.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3F(SEMA3F) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Semaphorin-3G(SEMA3G) ELISA kit

CSB-EL020986MO-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3G (SEMA3G) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Semaphorin-3G(SEMA3G) ELISA kit

1-CSB-EL020986MO
  • EUR 964.80
  • EUR 6118.80
  • EUR 3244.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3G(SEMA3G) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Semaphorin-4D(SEMA4D) ELISA kit

CSB-EL020990MO-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-4D (SEMA4D) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Semaphorin-4D(SEMA4D) ELISA kit

1-CSB-EL020990MO
  • EUR 964.80
  • EUR 6118.80
  • EUR 3244.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-4D(SEMA4D) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Semaphorin-7A(SEMA7A) ELISA kit

CSB-EL021000MO-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-7A (SEMA7A) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Semaphorin-7A(SEMA7A) ELISA kit

1-CSB-EL021000MO
  • EUR 964.80
  • EUR 6118.80
  • EUR 3244.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-7A(SEMA7A) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Semaphorin 3A(SEMA3A) ELISA kit

E03S0355-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3A(SEMA3A) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Two genes, LBH and SHF, confirmed decrease expression ranges in AD circumstances than management topics. That is in step with the gene expression ranges of each the genes in mouse which have been negatively correlated with Aβ accumulation. These outcomes, obtained from the integrative method, counsel that LBH and SHF are related to the AD pathogenesis.

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