Identification of fibronectin 1 as a candidate genetic modifier in a Col4a1 mutant mouse model of Gould syndrome
Collagen sort IV alpha 1 and alpha 2 (COL4A1 and COL4A2) are main parts of just about all basement membranes. COL4A1 and COL4A2 mutations trigger a multisystem dysfunction that may have an effect on any organ however usually entails the cerebral vasculature, eyes, kidneys and skeletal muscular tissues. In recent times, affected person advocacy and household help teams have united underneath the identify of Gould syndrome.
The manifestations of Gould syndrome are extremely variable, and animal research counsel that allelic heterogeneity and genetic context contribute to the scientific variability. We beforehand characterised a mouse mannequin of Gould syndrome attributable to a Col4a1 mutation by which the severities of ocular anterior phase dysgenesis (ASD), myopathy and intracerebral hemorrhage (ICH) have been depending on genetic background.
Right here, we carried out a genetic modifier display to offer perception into the mechanisms contributing to Gould syndrome pathogenesis and recognized a single locus [modifier of Gould syndrome 1 (MoGS1)] on Chromosome 1 that suppressed ASD.
A separate display confirmed that the identical locus ameliorated myopathy. Apparently, MoGS1 had no impact on ICH, suggesting that this phenotype might be mechanistically distinct. We refined the MoGS1 locus to a 4.three Mb interval containing 18 protein-coding genes, together with Fn1, which encodes the extracellular matrix part fibronectin 1. Molecular evaluation confirmed that the MoGS1 locus elevated Fn1 expression, elevating the chance that suppression is achieved by a compensatory extracellular mechanism.
Moreover, we discovered proof of elevated integrin-linked kinase ranges and focal adhesion kinase phosphorylation in Col4a1 mutant mice that’s partially restored by the MoGS1 locus, implicating the involvement of integrin signaling. Taken collectively, our outcomes counsel that tissue-specific mechanistic heterogeneity contributes to the variable expressivity of Gould syndrome and that perturbations in integrin signaling might play a job in ocular and muscular manifestations.
Dopaminergic Dysregulation in Syndromic Autism Spectrum Issues: Insights From Genetic Mouse Fashions
Autism spectrum dysfunction (ASD) is a neurodevelopmental dysfunction outlined by altered social interplay and communication, and repetitive, restricted, rigid behaviors. Roughly 1.5-2% of the overall inhabitants meet the diagnostic standards for ASD and a number of other mind areas together with the cortex, amygdala, cerebellum and basal ganglia have been implicated in ASD pathophysiology.
The midbrain dopamine system is a vital modulator of mobile and synaptic operate in a number of ASD-implicated mind areas through anatomically and functionally distinct dopaminergic projections. The dopamine speculation of ASD postulates that dysregulation of dopaminergic projection pathways might contribute to the behavioral manifestations of ASD, together with altered reward worth of social stimuli, adjustments in sensorimotor processing, and motor stereotypies.
On this overview, we look at the help for the concept that cell-autonomous adjustments in dopaminergic operate are a core part of ASD pathophysiology. We talk about the human literature supporting the involvement of altered dopamine signaling in ASD together with genetic, mind imaging and pharmacologic research.
We then concentrate on genetic mouse fashions of syndromic neurodevelopmental problems by which single gene mutations result in elevated threat for ASD. We spotlight research which have straight examined dopamine neuron quantity, morphology, physiology, or output in these fashions.
Total, we discover appreciable help for the concept that the dopamine system could also be dysregulated in syndromic ASDs; nevertheless, there doesn’t seem like a constant signature and a few fashions present elevated dopaminergic operate, whereas others have poor dopamine signaling.
We conclude that dopamine dysregulation is frequent in syndromic types of ASD however that the particular adjustments could also be distinctive to every genetic dysfunction and should not account for the complete spectrum of ASD-related manifestations.
A genetic mannequin to check O-GlcNAc biking in immortalized mouse embryonic fibroblasts.
O-GlcNAcylation is an plentiful posttranslational protein modification by which the monosaccharide O-GlcNAc is added to Ser/Thr residues by O-GlcNAc transferase and eliminated by O-GlcNAcase. Analyses of O-GlcNAc-mediated signaling and metabolic phenomena are sophisticated by components together with unsatisfactory inhibitors and loss-of-function cell strains missing an identical genetic backgrounds.
On this work, we generated immortalized WT, Oga knockout, and Ogt floxed allele (Ogt floxed) mouse embryonic fibroblast (MEF) cell strains with related genetic backgrounds. These strains will facilitate experiments and function a platform to check O-GlcNAc biking in mammals. As a take a look at paradigm, we used the immortalized MEF strains to research how adjustments in O-GlcNAcylation affected pathological phosphorylation of the tau protein.
The exercise of glycogen synthase kinase 3β (GSK3β), a kinase that phosphorylates tau, decreases when expressed in Oga knockout MEFs in contrast with WT cells. Phosphorylation at Thr231 in recombinant, tauopathy-associated tau with a proline-to-leucine mutation at place 301 (P301L) was altered when expressed in MEFs with altered O-GlcNAc biking.
In mixture, our knowledge help that O-GlcNAc biking not directly impacts tau phosphorylation at Thr231, however tau phosphorylation was extremely variable, even in genetically secure, immortalized MEF cells. The variable nature of tau phosphorylation noticed right here helps the necessity to use cells akin to these generated right here with genetically outlined lesions and related backgrounds to check advanced organic processes.
Built-in evaluation of human genetic affiliation research and mouse transcriptome suggests LBH and SHF genes as novel prone genes for amyloid-β accumulation in Alzheimer’s illness.
Alzheimer’s illness (AD) is a standard neurological illness that causes dementia in people. Though the experiences of related pathological genes have been rising, the molecular mechanism resulting in the buildup of amyloid-β (Aβ) in human mind continues to be not nicely understood.
To establish novel genes that trigger accumulation of Aβ in AD sufferers, we carried out an integrative evaluation by combining a human genetic affiliation research and transcriptome evaluation in mouse mind. First, we examined genome-wide gene expression ranges within the hippocampus, evaluating them to amyloid Aβ degree in mice with blended genetic backgrounds.
Subsequent, primarily based on a GWAS statistics obtained by a earlier research with human AD topics, we obtained gene-based statistics from the SNP-based statistics. We mixed p values from the 2 forms of evaluation throughout orthologous gene pairs in human and mouse into one p worth for every gene to judge AD susceptibility.
In consequence, we discovered 5 genes with vital p values on this built-in evaluation among the many 373 genes analyzed. We additionally examined the gene expression degree of those 5 genes within the hippocampus of unbiased human AD circumstances and management topics.
Semaphorin 6A (SEMA6A) Antibody |
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| 20-abx302320 | Abbexa |
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Semaphorin 6A Antibody / SEMA6A |
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| RQ5921 | NSJ Bioreagents | 100 ug | EUR 419 |
Mouse Semaphorin- 6A, Sema6a ELISA KIT |
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| ELI-52928m | Lifescience Market | 96 Tests | EUR 1038 |
Human Semaphorin 6A (SEMA6A)ELISA Kit |
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| 201-12-1088 | SunredBio | 96 tests | EUR 528 |
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Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
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Human Semaphorin- 6A, SEMA6A ELISA KIT |
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| ELI-52440h | Lifescience Market | 96 Tests | EUR 988.8 |
Human Semaphorin 6A(SEMA6A)ELISA Kit |
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| GA-E1104HM-48T | GenAsia Biotech | 48T | EUR 346.8 |
Human Semaphorin 6A(SEMA6A)ELISA Kit |
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| GA-E1104HM-96T | GenAsia Biotech | 96T | EUR 559.2 |
Human Semaphorin 6A(SEMA6A)ELISA Kit |
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| QY-E00788 | Qayee Biotechnology | 96T | EUR 433.2 |
Human Semaphorin 6A (SEMA6A)ELISA Kit |
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| YLA2513HU-48T | Shanghai YL Biotech | 48T | EUR 435 |
Human Semaphorin 6A (SEMA6A)ELISA Kit |
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| YLA2513HU-96T | Shanghai YL Biotech | 96T | EUR 562.5 |
Mouse anti-SAH 6a |
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| MA00306-50 | Arthus | 50µg | EUR 417.6 |
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Description: Mouse monoclonal antibody to S-Adenosylhomocysteine Clone 844-2 |
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Rabbit Polyclonal antibody Anti-CRBN |
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| Anti-CRBN | ImmunoStep | 50 µg | EUR 418.8 |
anti- Cytokeratin 6A antibody |
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| FNab02215 | FN Test | 100µg | EUR 658.5 |
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Description: Antibody raised against Cytokeratin 6A |
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Anti-Rab 6A Antibody |
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| A02911 | BosterBio | 100ul | EUR 476.4 |
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Description: Rabbit Polyclonal Antibody for Rab 6A Antibody (RAB6A) detection.tested for WB in Human, Mouse, Rat. |
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Anti-Cytokeratin 6A antibody |
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| PAab02215 | Lifescience Market | 100 ug | EUR 463.2 |
Anti-Rab 6A antibody |
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| STJ95302 | St John's Laboratory | 200 µl | EUR 236.4 |
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Description: Rabbit polyclonal to Rab 6A. |
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anti-Semaphorin 3D |
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| YF-PA22776 | Abfrontier | 50 ug | EUR 435.6 |
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Description: Mouse polyclonal to Semaphorin 3D |
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anti-Semaphorin 3D |
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| YF-PA22777 | Abfrontier | 100 ug | EUR 483.6 |
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Description: Rabbit polyclonal to Semaphorin 3D |
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anti-Semaphorin 3B |
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| YF-PA25020 | Abfrontier | 50 ul | EUR 400.8 |
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Description: Mouse polyclonal to Semaphorin 3B |
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anti-Semaphorin 7a |
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| YF-PA25109 | Abfrontier | 50 ul | EUR 400.8 |
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Description: Mouse polyclonal to Semaphorin 7a |
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anti-Semaphorin 3A |
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| YF-PA25559 | Abfrontier | 50 ul | EUR 400.8 |
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Description: Mouse polyclonal to Semaphorin 3A |
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anti-Semaphorin 3B |
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| YF-PA15485 | Abfrontier | 100 ug | EUR 483.6 |
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Description: Rabbit polyclonal to Semaphorin 3B |
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anti-Anti-Semaphorin 5A |
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| YF-PA25252 | Abfrontier | 50 ul | EUR 400.8 |
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Description: Mouse polyclonal to Anti-Semaphorin 5A |
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Keratin 6A Antibody / Cytokeratin 6A |
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| V8960-100UG | NSJ Bioreagents | 100ug | EUR 499 |
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Description: Cytokeratin 6 is an epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. This protein always paired with the type-I keratin K16. Cytokeratin 6 have been identified in epidermis only in samples from plantar glabrous skin while in hairy skin this keratin appeared to be absent in interfollicular epidermis but were clearly present in hair follicle outer root sheath, and this protein also consistently expressed in non-keratinizing stratified squamous epithelia. Among tumors, cytokeratin 6 is typically and strongly expressed in squamous cell carcinomas of different sites, preferentially in inner, maturing layers of the tumor cell nests. Cytokeratin 6 is always used with cytokeratin 5 and is a useful aid for classification of epithelioid mesotheliomas. |
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Keratin 6A Antibody / Cytokeratin 6A |
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| V8960-20UG | NSJ Bioreagents | 20ug | EUR 219 |
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Description: Cytokeratin 6 is an epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. This protein always paired with the type-I keratin K16. Cytokeratin 6 have been identified in epidermis only in samples from plantar glabrous skin while in hairy skin this keratin appeared to be absent in interfollicular epidermis but were clearly present in hair follicle outer root sheath, and this protein also consistently expressed in non-keratinizing stratified squamous epithelia. Among tumors, cytokeratin 6 is typically and strongly expressed in squamous cell carcinomas of different sites, preferentially in inner, maturing layers of the tumor cell nests. Cytokeratin 6 is always used with cytokeratin 5 and is a useful aid for classification of epithelioid mesotheliomas. |
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Keratin 6A Antibody / Cytokeratin 6A |
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| V8960SAF-100UG | NSJ Bioreagents | 100ug | EUR 499 |
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Description: Cytokeratin 6 is an epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. This protein always paired with the type-I keratin K16. Cytokeratin 6 have been identified in epidermis only in samples from plantar glabrous skin while in hairy skin this keratin appeared to be absent in interfollicular epidermis but were clearly present in hair follicle outer root sheath, and this protein also consistently expressed in non-keratinizing stratified squamous epithelia. Among tumors, cytokeratin 6 is typically and strongly expressed in squamous cell carcinomas of different sites, preferentially in inner, maturing layers of the tumor cell nests. Cytokeratin 6 is always used with cytokeratin 5 and is a useful aid for classification of epithelioid mesotheliomas. |
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CD6 |
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| 6A-100T | ImmunoStep | 100 test | EUR 418.8 |
anti- Cytokeratin 6A-specific antibody |
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| FNab02216 | FN Test | 100µg | EUR 658.5 |
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Description: Antibody raised against Cytokeratin 6A-specific |
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Anti-Cytokeratin 6A-specific antibody |
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| PAab02216 | Lifescience Market | 100 ug | EUR 463.2 |
Anti Mouse Semaphorin 3B Polyclonal Antibody |
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| KR100 | Sceti | each | EUR 778.8 |
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Description: The Anti Mouse Semaphorin 3B Polyclonal Antibody is available in Europe and for worldwide shipping via Gentaur. |
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Polyclonal Goat anti-GST α-form |
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| GST-ANTI-1 | Detroit R&D | 50 uL | EUR 336 |
Polyclonal Goat anti-GST μ-form |
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| GST-ANTI-2 | Detroit R&D | 50 uL | EUR 336 |
Polyclonal Goat anti-GST p-form |
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| GST-ANTI-3 | Detroit R&D | 50 uL | EUR 336 |
Peptide 6A |
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| H-6905.0005 | Bachem | 5.0mg | EUR 356.4 |
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Description: Sum Formula: C23H43N9O6; CAS# [73549-32-3] |
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Peptide 6A |
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| H-6905.0025 | Bachem | 25.0mg | EUR 1311.6 |
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Description: Sum Formula: C23H43N9O6; CAS# [73549-32-3] |
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6a-Hydroxymaackiain |
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| TB02758 | ChemNorm | 5mg | EUR 1016.4 |
6a-Senecioyloxychaparrin |
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| TBZ0849 | ChemNorm | unit | Ask for price |
6a-Hydroxyeurycomalactone |
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| TBZ1429 | ChemNorm | unit | Ask for price |
Anti-Semaphorin 5A antibody |
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| STJ70970 | St John's Laboratory | 100 µg | EUR 430.8 |
Anti-Semaphorin 7a (3D3) |
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| YF-MA16372 | Abfrontier | 100 ug | EUR 435.6 |
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Description: Mouse monoclonal to Semaphorin 7a |
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Anti-Semaphorin 7a (1G1) |
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| YF-MA16373 | Abfrontier | 100 ug | EUR 435.6 |
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Description: Mouse monoclonal to Semaphorin 7a |
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Anti-Semaphorin 3A (5G9) |
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| YF-MA17274 | Abfrontier | 50 ug | EUR 435.6 |
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Description: Mouse monoclonal to Semaphorin 3A |
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Anti-Semaphorin 4D (3B4) |
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| YF-MA17342 | Abfrontier | 100 ug | EUR 435.6 |
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Description: Mouse monoclonal to Semaphorin 4D |
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Anti-Semaphorin 3B/SEMA3B Antibody |
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| A06559-1 | BosterBio | 100ug/vial | EUR 352.8 |
Anti-SEMA4A/Semaphorin 4A Antibody |
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| A06779-1 | BosterBio | 100ul | EUR 476.4 |
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Description: Rabbit Polyclonal Antibody for SEMA4A Antibody (SEMA4A) detection.tested for WB in Human, Mouse, Rat, Monkey. |
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Anti-Semaphorin 3E/SEMA3E Antibody |
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| A06937-2 | BosterBio | 100ug/vial | EUR 352.8 |
Anti-SEMA4C/Semaphorin 4C Antibody |
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| A08069 | BosterBio | 100ul | EUR 476.4 |
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Description: Rabbit Polyclonal SEMA4C/Semaphorin 4C Antibody. Validated in WB and tested in Human. |
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Anti-Semaphorin 3A/SEMA3A Antibody |
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| A01761-1 | BosterBio | 100ug/vial | EUR 352.8 |
Anti-Semaphorin 3c/SEMA3C Antibody |
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| A06444-1 | BosterBio | 100ug/vial | EUR 352.8 |
Anti-Semaphorin 3A/SEMA3A Antibody |
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| PB9353 | BosterBio | 100ug/vial | EUR 352.8 |
Anti-Semaphorin 3E (internal) antibody |
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| STJ71055 | St John's Laboratory | 100 µg | EUR 430.8 |
Cytokeratin 6a Antibody |
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| DF7789 | Affbiotech | 200ul | EUR 420 |
Estriol 6a antibody |
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| 20-1630 | Fitzgerald | 100 ul | EUR 1054.8 |
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Description: Sheep polyclonal Estriol 6a antibody |
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Cytokeratin 6A Antibody |
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| abx232215-100ug | Abbexa | 100 ug | EUR 610.8 |
pFlag- CMV- 6a |
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| PVT10705 | Lifescience Market | 2 ug | EUR 361.2 |
Cytokeratin 6A Antibody |
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| V7912-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
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Description: This MAb recognizes a protein of 56kDa, identified as cytokeratin 6A (KRT6A). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express KRT6 and KRT16. KRT6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. |
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Cytokeratin 6A Antibody |
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| V7912-20UG | NSJ Bioreagents | 20 ug | EUR 219 |
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Description: This MAb recognizes a protein of 56kDa, identified as cytokeratin 6A (KRT6A). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express KRT6 and KRT16. KRT6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. |
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Cytokeratin 6A Antibody |
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| V7912SAF-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
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Description: This MAb recognizes a protein of 56kDa, identified as cytokeratin 6A (KRT6A). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express KRT6 and KRT16. KRT6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. |
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Growth Medium 6A |
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| 79542 | BPS Bioscience | 500 ml | EUR 650 |
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Description: This liquid Growth Medium is a complete medium optimized to culture select BPS Bioscience cell lines. |
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Mouse Keratin 6A (KRT6A) ELISA Kit |
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| abx514580-96tests | Abbexa | 96 tests | EUR 886.8 |
Mouse Semaphorin 7A ELISA kit |
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| E03S0083-192T | BlueGene | 192 tests | EUR 1524 |
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Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 7A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse Semaphorin 7A ELISA kit |
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| E03S0083-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
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Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 7A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse Semaphorin 7A ELISA kit |
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| E03S0083-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
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Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 7A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse Semaphorin 3 ELISA kit |
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| E03S0084-192T | BlueGene | 192 tests | EUR 1524 |
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Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3
in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse Semaphorin 3 ELISA kit |
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| E03S0084-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
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Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3
in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse Semaphorin 3 ELISA kit |
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| E03S0084-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
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Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3
in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse Semaphorin 4D ELISA kit |
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| E03S0300-192T | BlueGene | 192 tests | EUR 1524 |
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Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 4D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse Semaphorin 4D ELISA kit |
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| E03S0300-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
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Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 4D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse Semaphorin 4D ELISA kit |
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| E03S0300-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
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Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 4D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse Semaphorin 6D ELISA kit |
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| E03S0464-192T | BlueGene | 192 tests | EUR 1524 |
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Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 6D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse Semaphorin 6D ELISA kit |
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| E03S0464-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
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Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 6D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse Semaphorin 6D ELISA kit |
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| E03S0464-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
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Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 6D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse semaphorin 3G ELISA kit |
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| E03S0470-192T | BlueGene | 192 tests | EUR 1524 |
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Description: A sandwich ELISA for quantitative measurement of Mouse semaphorin 3G in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse semaphorin 3G ELISA kit |
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| E03S0470-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
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Description: A sandwich ELISA for quantitative measurement of Mouse semaphorin 3G in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse semaphorin 3G ELISA kit |
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| E03S0470-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
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Description: A sandwich ELISA for quantitative measurement of Mouse semaphorin 3G in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse Semaphorin 3A (SEMA3A) Protein |
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| 20-abx069022 | Abbexa |
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Mouse Semaphorin 3E (SEMA3E) Protein |
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| 20-abx069024 | Abbexa |
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Mouse Semaphorin 4B (SEMA4B) Protein |
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| 20-abx069029 | Abbexa |
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Mouse Semaphorin 5B (SEMA5B) Protein |
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| 20-abx069034 | Abbexa |
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Mouse Semaphorin 7A (SEMA7A) Protein |
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| 20-abx167332 | Abbexa |
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Mouse Semaphorin 4D (SEMA4D) Protein |
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| 20-abx167383 | Abbexa |
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Mouse Semaphorin- 3G ELISA Kit |
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| ELA-E7736m | Lifescience Market | 96 Tests | EUR 1038 |
Semaphorin 5A |
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| P41026 | Neuromics | 100 ug Blocking Peptide | EUR 286.8 |
Semaphorin 7A |
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| MO15041 | Neuromics | 500 ug | EUR 615.6 |
Semaphorin 7A |
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| GT15076 | Neuromics | 100 ug | EUR 646.8 |
Semaphorin 3C |
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| GT15077 | Neuromics | 100 ug | EUR 631.2 |
Semaphorin 6B |
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| GT15165 | Neuromics | 100 ug | EUR 631.2 |
Semaphorin 5A |
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| GT41026 | Neuromics | 100 ug | EUR 568.8 |
Semaphorin 3B |
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| RA25088 | Neuromics | 50 ul | EUR 568.8 |
Rab 6A Polyclonal Antibody |
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| ES6964-100ul | ELK Biotech | 100ul | EUR 334.8 |
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Description: A Rabbit Polyclonal antibody against Rab 6A from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
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Rab 6A Polyclonal Antibody |
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| ES6964-50ul | ELK Biotech | 50ul | EUR 248.4 |
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Description: A Rabbit Polyclonal antibody against Rab 6A from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
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Rab 6A Polyclonal Antibody |
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| 41378-100ul | SAB | 100ul | EUR 302.4 |
Rab 6A Polyclonal Antibody |
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| 41378-50ul | SAB | 50ul | EUR 224.4 |
Rab 6A Polyclonal Antibody |
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| ABP55965-003ml | Abbkine | 0.03ml | EUR 189.6 |
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Description: A polyclonal antibody for detection of Rab 6A from Human, Mouse, Rat. This Rab 6A antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Rab 6A at AA range: 90-170 |
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Rab 6A Polyclonal Antibody |
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| ABP55965-01ml | Abbkine | 0.1ml | EUR 346.8 |
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Description: A polyclonal antibody for detection of Rab 6A from Human, Mouse, Rat. This Rab 6A antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Rab 6A at AA range: 90-170 |
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Rab 6A Polyclonal Antibody |
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| ABP55965-02ml | Abbkine | 0.2ml | EUR 496.8 |
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Description: A polyclonal antibody for detection of Rab 6A from Human, Mouse, Rat. This Rab 6A antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Rab 6A at AA range: 90-170 |
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Keratin 6A (KRT6A) Antibody |
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| 20-abx100825 | Abbexa |
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Keratin 6A (KRT6A) Antibody |
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| 20-abx100826 | Abbexa |
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Keratin 6A (KRT6A) Antibody |
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| 20-abx100827 | Abbexa |
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Keratin 6A (KRT6A) Antibody |
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| 20-abx109957 | Abbexa |
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Keratin 6A (KRT6A) Antibody |
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| 20-abx159587 | Abbexa |
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Keratin 6A (KRT6A) Antibody |
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| abx146382-100ug | Abbexa | 100 ug | EUR 469.2 |
Keratin 6A (KRT6A) Antibody |
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| 20-abx113347 | Abbexa |
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Keratin 6A (KRT6A) Antibody |
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| 20-abx005878 | Abbexa |
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Keratin 6A (KRT6A) Antibody |
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| 20-abx002875 | Abbexa |
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Keratin 6A (KRT6A) Antibody |
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| abx029191-400ul | Abbexa | 400 ul | EUR 627.6 |
Keratin 6A (KRT6A) Antibody |
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| abx029191-80l | Abbexa | 80 µl | EUR 343.2 |
PDE 6A Polyclonal Antibody |
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| ABP-PAB-31042 | Allele Biotech | 50 ug | Ask for price |
Cytokeratin 6A-specific Antibody |
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| abx232216-100ug | Abbexa | 100 ug | EUR 610.8 |
Keratin 6A (KRT6A) Antibody |
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| 20-abx322514 | Abbexa |
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Keratin 6A (KRT6A) Antibody |
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| 20-abx322515 | Abbexa |
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Keratin 6A (KRT6A) Antibody |
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| 20-abx304308 | Abbexa |
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Keratin 6A (KRT6A) Antibody |
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| 20-abx214450 | Abbexa |
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Keratin 6A (KRT6A) Antibody |
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| 20-abx214451 | Abbexa |
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Recombinant Keratin 6A (KRT6A) |
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| 4-RPD234Hu01 | Cloud-Clone |
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Description: Recombinant Human Keratin 6A expressed in: E.coli |
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Recombinant Keratin 6A (KRT6A) |
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| 4-RPD234Ra01 | Cloud-Clone |
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Description: Recombinant Rat Keratin 6A expressed in: E.coli |
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Anti Mouse Semaphorin 4A Monoclonal Antibody (Clone No. HIAT-2) |
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| KO401 | Sceti | each | EUR 856.8 |
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Description: The Anti Mouse Semaphorin 4A Monoclonal Antibody (Clone No. HIAT-2) is available in Europe and for worldwide shipping via Gentaur. |
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Anti Mouse Semaphorin 7A Monoclonal Antibody (Clone No. SKK-7) |
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| KO402 | Sceti | each | EUR 856.8 |
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Description: The Anti Mouse Semaphorin 7A Monoclonal Antibody (Clone No. SKK-7) is available in Europe and for worldwide shipping via Gentaur. |
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Mouse Semaphorin-3A(SEMA3A) ELISA kit |
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| CSB-EL020980MO-24T | Cusabio | 1 plate of 24 wells | EUR 198 |
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Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3A (SEMA3A) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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Mouse Semaphorin-3A(SEMA3A) ELISA kit |
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| 1-CSB-EL020980MO | Cusabio |
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Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3A(SEMA3A) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
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Mouse Semaphorin-3B(SEMA3B) ELISA kit |
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| CSB-EL020981MO-24T | Cusabio | 1 plate of 24 wells | EUR 198 |
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Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3B (SEMA3B) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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Mouse Semaphorin-3B(SEMA3B) ELISA kit |
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| 1-CSB-EL020981MO | Cusabio |
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Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3B(SEMA3B) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
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Mouse Semaphorin-3D(SEMA3D) ELISA kit |
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| CSB-EL020983MO-24T | Cusabio | 1 plate of 24 wells | EUR 198 |
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Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3D (SEMA3D) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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Mouse Semaphorin-3D(SEMA3D) ELISA kit |
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| 1-CSB-EL020983MO | Cusabio |
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Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3D(SEMA3D) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
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Mouse Semaphorin-3E(SEMA3E) ELISA kit |
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| CSB-EL020984MO-24T | Cusabio | 1 plate of 24 wells | EUR 198 |
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Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3E (SEMA3E) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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Two genes, LBH and SHF, confirmed decrease expression ranges in AD circumstances than management topics. That is in step with the gene expression ranges of each the genes in mouse which have been negatively correlated with Aβ accumulation. These outcomes, obtained from the integrative method, counsel that LBH and SHF are related to the AD pathogenesis.
