
Identification of fibronectin 1 as a candidate genetic modifier in a Col4a1 mutant mouse model of Gould syndrome
Danielle
- 0
Collagen sort IV alpha 1 and alpha 2 (COL4A1 and COL4A2) are main parts of just about all basement membranes. COL4A1 and COL4A2 mutations trigger a multisystem dysfunction that may have an effect on any organ however usually entails the cerebral vasculature, eyes, kidneys and skeletal muscular tissues. In recent times, affected person advocacy and household help teams have united underneath the identify of Gould syndrome.
The manifestations of Gould syndrome are extremely variable, and animal research counsel that allelic heterogeneity and genetic context contribute to the scientific variability. We beforehand characterised a mouse mannequin of Gould syndrome attributable to a Col4a1 mutation by which the severities of ocular anterior phase dysgenesis (ASD), myopathy and intracerebral hemorrhage (ICH) have been depending on genetic background.
Right here, we carried out a genetic modifier display to offer perception into the mechanisms contributing to Gould syndrome pathogenesis and recognized a single locus [modifier of Gould syndrome 1 (MoGS1)] on Chromosome 1 that suppressed ASD.
A separate display confirmed that the identical locus ameliorated myopathy. Apparently, MoGS1 had no impact on ICH, suggesting that this phenotype might be mechanistically distinct. We refined the MoGS1 locus to a 4.three Mb interval containing 18 protein-coding genes, together with Fn1, which encodes the extracellular matrix part fibronectin 1. Molecular evaluation confirmed that the MoGS1 locus elevated Fn1 expression, elevating the chance that suppression is achieved by a compensatory extracellular mechanism.
Moreover, we discovered proof of elevated integrin-linked kinase ranges and focal adhesion kinase phosphorylation in Col4a1 mutant mice that’s partially restored by the MoGS1 locus, implicating the involvement of integrin signaling. Taken collectively, our outcomes counsel that tissue-specific mechanistic heterogeneity contributes to the variable expressivity of Gould syndrome and that perturbations in integrin signaling might play a job in ocular and muscular manifestations.
Dopaminergic Dysregulation in Syndromic Autism Spectrum Issues: Insights From Genetic Mouse Fashions
Autism spectrum dysfunction (ASD) is a neurodevelopmental dysfunction outlined by altered social interplay and communication, and repetitive, restricted, rigid behaviors. Roughly 1.5-2% of the overall inhabitants meet the diagnostic standards for ASD and a number of other mind areas together with the cortex, amygdala, cerebellum and basal ganglia have been implicated in ASD pathophysiology.
The midbrain dopamine system is a vital modulator of mobile and synaptic operate in a number of ASD-implicated mind areas through anatomically and functionally distinct dopaminergic projections. The dopamine speculation of ASD postulates that dysregulation of dopaminergic projection pathways might contribute to the behavioral manifestations of ASD, together with altered reward worth of social stimuli, adjustments in sensorimotor processing, and motor stereotypies.
On this overview, we look at the help for the concept that cell-autonomous adjustments in dopaminergic operate are a core part of ASD pathophysiology. We talk about the human literature supporting the involvement of altered dopamine signaling in ASD together with genetic, mind imaging and pharmacologic research.
We then concentrate on genetic mouse fashions of syndromic neurodevelopmental problems by which single gene mutations result in elevated threat for ASD. We spotlight research which have straight examined dopamine neuron quantity, morphology, physiology, or output in these fashions.
Total, we discover appreciable help for the concept that the dopamine system could also be dysregulated in syndromic ASDs; nevertheless, there doesn’t seem like a constant signature and a few fashions present elevated dopaminergic operate, whereas others have poor dopamine signaling.
We conclude that dopamine dysregulation is frequent in syndromic types of ASD however that the particular adjustments could also be distinctive to every genetic dysfunction and should not account for the complete spectrum of ASD-related manifestations.
A genetic mannequin to check O-GlcNAc biking in immortalized mouse embryonic fibroblasts.
O-GlcNAcylation is an plentiful posttranslational protein modification by which the monosaccharide O-GlcNAc is added to Ser/Thr residues by O-GlcNAc transferase and eliminated by O-GlcNAcase. Analyses of O-GlcNAc-mediated signaling and metabolic phenomena are sophisticated by components together with unsatisfactory inhibitors and loss-of-function cell strains missing an identical genetic backgrounds.
On this work, we generated immortalized WT, Oga knockout, and Ogt floxed allele (Ogt floxed) mouse embryonic fibroblast (MEF) cell strains with related genetic backgrounds. These strains will facilitate experiments and function a platform to check O-GlcNAc biking in mammals. As a take a look at paradigm, we used the immortalized MEF strains to research how adjustments in O-GlcNAcylation affected pathological phosphorylation of the tau protein.
The exercise of glycogen synthase kinase 3β (GSK3β), a kinase that phosphorylates tau, decreases when expressed in Oga knockout MEFs in contrast with WT cells. Phosphorylation at Thr231 in recombinant, tauopathy-associated tau with a proline-to-leucine mutation at place 301 (P301L) was altered when expressed in MEFs with altered O-GlcNAc biking.
In mixture, our knowledge help that O-GlcNAc biking not directly impacts tau phosphorylation at Thr231, however tau phosphorylation was extremely variable, even in genetically secure, immortalized MEF cells. The variable nature of tau phosphorylation noticed right here helps the necessity to use cells akin to these generated right here with genetically outlined lesions and related backgrounds to check advanced organic processes.

Built-in evaluation of human genetic affiliation research and mouse transcriptome suggests LBH and SHF genes as novel prone genes for amyloid-β accumulation in Alzheimer’s illness.
Alzheimer’s illness (AD) is a standard neurological illness that causes dementia in people. Though the experiences of related pathological genes have been rising, the molecular mechanism resulting in the buildup of amyloid-β (Aβ) in human mind continues to be not nicely understood.
To establish novel genes that trigger accumulation of Aβ in AD sufferers, we carried out an integrative evaluation by combining a human genetic affiliation research and transcriptome evaluation in mouse mind. First, we examined genome-wide gene expression ranges within the hippocampus, evaluating them to amyloid Aβ degree in mice with blended genetic backgrounds.
Subsequent, primarily based on a GWAS statistics obtained by a earlier research with human AD topics, we obtained gene-based statistics from the SNP-based statistics. We mixed p values from the 2 forms of evaluation throughout orthologous gene pairs in human and mouse into one p worth for every gene to judge AD susceptibility.
In consequence, we discovered 5 genes with vital p values on this built-in evaluation among the many 373 genes analyzed. We additionally examined the gene expression degree of those 5 genes within the hippocampus of unbiased human AD circumstances and management topics.
Semaphorin 6A (SEMA6A) Antibody |
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abx031680-400ul | Abbexa | 400 ul | EUR 627.6 |
Semaphorin 6A (SEMA6A) Antibody |
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abx031680-80l | Abbexa | 80 µl | EUR 343.2 |
Semaphorin 6A (SEMA6A) Antibody |
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20-abx302320 | Abbexa |
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Semaphorin 6A Antibody / SEMA6A |
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RQ5921 | NSJ Bioreagents | 100 ug | EUR 356.15 |
Description: SEMA6A belongs to a subfamily characterized by an extracellular semaphorin domain, a transmembrane domain, and a long cytoplasmic tail. Members of this class can repel sympathetic and dorsal root ganglion axons in vitro, consistent with a traditional role as guidance signals. However, the length of the cytoplasmic tail, which includes an EVL-binding site in SEMA6A and an Src-binding site in SEMA6B, suggests that these semaphorins may also function as receptors. SEMA6A is expressed in developing neural tissue and is required for proper development of the thalamocortical projection. SEMA6A directly links the Ena/VASP and the semaphorin protein families since the SEMA6A protein is capable of selective binding to the protein EVL (Ena/VASP-like protein). |
Rat Semaphorin 6A ELISA Kit |
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IRTSEMA6AKT | Innovative research | each | EUR 702 |
Description: Rat Semaphorin 6A ELISA Kit |
Human Semaphorin 6A (SEMA6A)ELISA Kit |
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201-12-1088 | SunredBio | 96 tests | EUR 528 |
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
Human Semaphorin- 6A, SEMA6A ELISA KIT |
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ELI-52440h | Lifescience Market | 96 Tests | EUR 988.8 |
Human Semaphorin 6A(SEMA6A)ELISA Kit |
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GA-E1104HM-48T | GenAsia Biotech | 48T | EUR 346.8 |
Human Semaphorin 6A(SEMA6A)ELISA Kit |
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GA-E1104HM-96T | GenAsia Biotech | 96T | EUR 559.2 |
Human Semaphorin 6A(SEMA6A)ELISA Kit |
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QY-E00788 | Qayee Biotechnology | 96T | EUR 433.2 |
Human Semaphorin 6A (SEMA6A)ELISA Kit |
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YLA2513HU-48T | Shanghai YL Biotech | 48T | EUR 435 |
Human Semaphorin 6A (SEMA6A)ELISA Kit |
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YLA2513HU-96T | Shanghai YL Biotech | 96T | EUR 562.5 |
Anti Mouse Semaphorin 3B Polyclonal Antibody |
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KR100 | Sceti | each | EUR 778.8 |
Description: The Anti Mouse Semaphorin 3B Polyclonal Antibody is available in Europe and for worldwide shipping via Gentaur. |
Mouse Semaphorin 7A ELISA kit |
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E03S0083-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 7A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Semaphorin 7A ELISA kit |
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E03S0083-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 7A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Semaphorin 7A ELISA kit |
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E03S0083-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 7A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Semaphorin 3 ELISA kit |
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E03S0084-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3
in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Semaphorin 3 ELISA kit |
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E03S0084-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3
in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Semaphorin 3 ELISA kit |
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E03S0084-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3
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Mouse Semaphorin 4D ELISA kit |
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E03S0300-192T | BlueGene | 192 tests | EUR 1524 |
Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 4D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Semaphorin 4D ELISA kit |
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E03S0300-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 4D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Semaphorin 4D ELISA kit |
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E03S0300-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 4D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Semaphorin 6D ELISA kit |
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E03S0464-192T | BlueGene | 192 tests | EUR 1524 |
Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 6D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Semaphorin 6D ELISA kit |
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E03S0464-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 6D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Semaphorin 6D ELISA kit |
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E03S0464-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 6D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse semaphorin 3G ELISA kit |
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E03S0470-192T | BlueGene | 192 tests | EUR 1524 |
Description: A sandwich ELISA for quantitative measurement of Mouse semaphorin 3G in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse semaphorin 3G ELISA kit |
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E03S0470-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A sandwich ELISA for quantitative measurement of Mouse semaphorin 3G in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse semaphorin 3G ELISA kit |
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E03S0470-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A sandwich ELISA for quantitative measurement of Mouse semaphorin 3G in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Semaphorin- 3G ELISA Kit |
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ELA-E7736m | Lifescience Market | 96 Tests | EUR 1038 |
Mouse Semaphorin 3E ELISA Kit |
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IMSSEMA3EKT | Innovative research | each | EUR 820 |
Description: Mouse Semaphorin 3E ELISA Kit |
Mouse Semaphorin 3F ELISA Kit |
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IMSSEMA3FKT | Innovative research | each | EUR 890 |
Description: Mouse Semaphorin 3F ELISA Kit |
Mouse Semaphorin 4G ELISA Kit |
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IMSSEMA4GKT | Innovative research | each | EUR 702 |
Description: Mouse Semaphorin 4G ELISA Kit |
Mouse Semaphorin 6C ELISA Kit |
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IMSSEMA6CKT | Innovative research | each | EUR 890 |
Description: Mouse Semaphorin 6C ELISA Kit |
Mouse Semaphorin 3A (SEMA3A) Protein |
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20-abx069022 | Abbexa |
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Mouse Semaphorin 3E (SEMA3E) Protein |
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20-abx069024 | Abbexa |
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Mouse Semaphorin 4B (SEMA4B) Protein |
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20-abx069029 | Abbexa |
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Mouse Semaphorin 5B (SEMA5B) Protein |
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20-abx069034 | Abbexa |
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Mouse Semaphorin 7A (SEMA7A) Protein |
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20-abx167332 | Abbexa |
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Mouse Semaphorin 4D (SEMA4D) Protein |
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20-abx167383 | Abbexa |
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Mouse Semaphorin-3A(SEMA3A) ELISA kit |
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CSB-EL020980MO-24T | Cusabio | 1 plate of 24 wells | EUR 198 |
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3A (SEMA3A) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
Mouse Semaphorin-3A(SEMA3A) ELISA kit |
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1-CSB-EL020980MO | Cusabio |
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Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3A(SEMA3A) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
Mouse Semaphorin-3B(SEMA3B) ELISA kit |
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CSB-EL020981MO-24T | Cusabio | 1 plate of 24 wells | EUR 198 |
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3B (SEMA3B) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
Mouse Semaphorin-3B(SEMA3B) ELISA kit |
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1-CSB-EL020981MO | Cusabio |
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Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3B(SEMA3B) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
Mouse Semaphorin-3D(SEMA3D) ELISA kit |
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CSB-EL020983MO-24T | Cusabio | 1 plate of 24 wells | EUR 198 |
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3D (SEMA3D) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
Mouse Semaphorin-3D(SEMA3D) ELISA kit |
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1-CSB-EL020983MO | Cusabio |
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Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3D(SEMA3D) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
Mouse Semaphorin-3E(SEMA3E) ELISA kit |
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CSB-EL020984MO-24T | Cusabio | 1 plate of 24 wells | EUR 198 |
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3E (SEMA3E) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
Mouse Semaphorin-3E(SEMA3E) ELISA kit |
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1-CSB-EL020984MO | Cusabio |
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Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3E(SEMA3E) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
Mouse Semaphorin-3F(SEMA3F) ELISA kit |
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CSB-EL020985MO-24T | Cusabio | 1 plate of 24 wells | EUR 198 |
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3F (SEMA3F) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
Mouse Semaphorin-3F(SEMA3F) ELISA kit |
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1-CSB-EL020985MO | Cusabio |
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Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3F(SEMA3F) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
Mouse Semaphorin-3G(SEMA3G) ELISA kit |
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CSB-EL020986MO-24T | Cusabio | 1 plate of 24 wells | EUR 198 |
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3G (SEMA3G) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
Mouse Semaphorin-3G(SEMA3G) ELISA kit |
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1-CSB-EL020986MO | Cusabio |
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Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-3G(SEMA3G) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
Mouse Semaphorin-4D(SEMA4D) ELISA kit |
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CSB-EL020990MO-24T | Cusabio | 1 plate of 24 wells | EUR 198 |
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-4D (SEMA4D) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
Mouse Semaphorin-4D(SEMA4D) ELISA kit |
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1-CSB-EL020990MO | Cusabio |
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Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-4D(SEMA4D) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
Mouse Semaphorin-7A(SEMA7A) ELISA kit |
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CSB-EL021000MO-24T | Cusabio | 1 plate of 24 wells | EUR 198 |
Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-7A (SEMA7A) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
Mouse Semaphorin-7A(SEMA7A) ELISA kit |
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1-CSB-EL021000MO | Cusabio |
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Description: Quantitativesandwich ELISA kit for measuring Mouse Semaphorin-7A(SEMA7A) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
Mouse Sema3a/ Semaphorin-3A ELISA Kit |
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E1322Mo | Sunlong | 1 Kit | EUR 685.2 |
Mouse Sema3f/ Semaphorin-3F ELISA Kit |
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E1323Mo | Sunlong | 1 Kit | EUR 685.2 |
Mouse Sema3g/ Semaphorin-3G ELISA Kit |
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E1324Mo | Sunlong | 1 Kit | EUR 685.2 |
Mouse Sema3g(Semaphorin-3G) ELISA Kit |
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EM0738 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.15 ng/ml |
Mouse Sema3a(Semaphorin-3A) ELISA Kit |
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EM0752 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 9.375pg/ml |
Mouse Sema3f(Semaphorin-3F) ELISA Kit |
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EM0753 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.188 ng/ml |
Mouse Semaphorin-3A (SEMA3A) ELISA Kit |
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KTE70462-96T5 | Abbkine | 96 T×5 | EUR 2809 |
Description: Mouse Semaphorin-3A (SEMA3A) ELISA Kit employs a two-site sandwich ELISA to quantitate SEMA3A in samples. |
Mouse Semaphorin-3A (SEMA3A) ELISA Kit |
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KTE70462-96T50 | Abbkine | 96 T×50 | EUR 26209 |
Description: Mouse Semaphorin-3A (SEMA3A) ELISA Kit employs a two-site sandwich ELISA to quantitate SEMA3A in samples. |
Mouse Semaphorin-3A(SEMA3A) ELISA kit |
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EKC41905-48T | Biomatik Corporation | 48T | EUR 535.99 |
Mouse Semaphorin-3A(SEMA3A) ELISA kit |
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EKC41905-5x96T | Biomatik Corporation | 5x96T | EUR 3637.08 |
Mouse Semaphorin-3A(SEMA3A) ELISA kit |
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EKC41905-96T | Biomatik Corporation | 96T | EUR 765.7 |
Mouse Semaphorin-3F(SEMA3F) ELISA kit |
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EKC41907-48T | Biomatik Corporation | 48T | EUR 535.99 |
Mouse Semaphorin-3F(SEMA3F) ELISA kit |
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EKC41907-5x96T | Biomatik Corporation | 5x96T | EUR 3637.08 |
Mouse Semaphorin-3F(SEMA3F) ELISA kit |
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EKC41907-96T | Biomatik Corporation | 96T | EUR 765.7 |
Mouse Semaphorin-3D(SEMA3D) ELISA kit |
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EKC37784-48T | Biomatik Corporation | 48T | EUR 535.99 |
Mouse Semaphorin-3D(SEMA3D) ELISA kit |
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EKC37784-5x96T | Biomatik Corporation | 5x96T | EUR 3637.08 |
Mouse Semaphorin-3D(SEMA3D) ELISA kit |
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EKC37784-96T | Biomatik Corporation | 96T | EUR 765.7 |
Mouse SEMA3C (Semaphorin-3C) ELISA Kit |
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EKE61835-5x96T | Biomatik Corporation | 5x96T | EUR 3124.08 |
Mouse SEMA3C (Semaphorin-3C) ELISA Kit |
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EKE61835-96T | Biomatik Corporation | 96T | EUR 657.7 |
Mouse Sema3a(Semaphorin-3A) ELISA Kit |
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EKF59118-48T | Biomatik Corporation | 48T | EUR 396.9 |
Mouse Sema3a(Semaphorin-3A) ELISA Kit |
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EKF59118-5x96T | Biomatik Corporation | 5x96T | EUR 2693.25 |
Mouse Sema3a(Semaphorin-3A) ELISA Kit |
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EKF59118-96T | Biomatik Corporation | 96T | EUR 567 |
ELISA kit for Mouse Semaphorin-3A |
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EK4463 | SAB | 96 tests | EUR 663.6 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse Semaphorin-3A in samples from serum, plasma, tissue homogenates and other biological fluids. |
ELISA kit for Mouse Semaphorin-3F |
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EK4467 | SAB | 96 tests | EUR 663.6 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse Semaphorin-3F in samples from serum, plasma, tissue homogenates and other biological fluids. |
Mouse Semaphorin 7A (SEMA7A) CLIA Kit |
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abx196261-96tests | Abbexa | 96 tests | EUR 990 |
Mouse Semaphorin 4D (SEMA4D) CLIA Kit |
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20-abx492750 | Abbexa |
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Mouse Semaphorin 7A (SEMA7A) CLIA Kit |
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20-abx492762 | Abbexa |
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Mouse Semaphorin 3A (SEMA3A) CLIA Kit |
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20-abx495984 | Abbexa |
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Mouse Semaphorin 3E (SEMA3E) CLIA Kit |
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20-abx495989 | Abbexa |
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Mouse Semaphorin 3F (SEMA3F) CLIA Kit |
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20-abx495993 | Abbexa |
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Mouse Semaphorin 4D (SEMA4D) ELISA Kit |
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20-abx258487 | Abbexa |
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Mouse Semaphorin 3F (SEMA3F) ELISA Kit |
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20-abx258657 | Abbexa |
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Mouse Semaphorin 7A (SEMA7A) ELISA Kit |
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abx254410-96tests | Abbexa | 96 tests | EUR 848.4 |
Mouse Semaphorin 3G (SEMA3G) ELISA Kit |
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abx255086-96tests | Abbexa | 96 tests | EUR 801.6 |
Mouse Semaphorin 3A (SEMA3A) ELISA Kit |
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abx255100-96tests | Abbexa | 96 tests | EUR 895.2 |
Mouse Semaphorin 3F (SEMA3F) ELISA Kit |
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abx255101-96tests | Abbexa | 96 tests | EUR 801.6 |
Mouse Semaphorin 3A (SEMA3A) ELISA Kit |
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20-abx154655 | Abbexa |
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Mouse Semaphorin 3E (SEMA3E) ELISA Kit |
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20-abx154656 | Abbexa |
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Mouse Semaphorin 7A (SEMA7A) ELISA Kit |
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20-abx154657 | Abbexa |
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Mouse Semaphorin 3E (SEMA3E) ELISA Kit |
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abx572536-96tests | Abbexa | 96 tests | EUR 801.6 |
Mouse Semaphorin 4D (SEMA4D) ELISA Kit |
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abx352594-96tests | Abbexa | 96 tests | EUR 943.2 |
Mouse Semaphorin 3C (SEMA3C) ELISA Kit |
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abx353175-96tests | Abbexa | 96 tests | EUR 943.2 |
Mouse Semaphorin 5A (SEMA5A) ELISA Kit |
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abx517654-96tests | Abbexa | 96 tests | EUR 801.6 |
Mouse Semaphorin 3A (SEMA3A) ELISA Kit |
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abx519931-96tests | Abbexa | 96 tests | EUR 801.6 |
Mouse Semaphorin 3B (SEMA3B) ELISA Kit |
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abx519934-96tests | Abbexa | 96 tests | EUR 801.6 |
Mouse Semaphorin 3C (SEMA3C) ELISA Kit |
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abx519938-96tests | Abbexa | 96 tests | EUR 801.6 |
Mouse Semaphorin 4D (SEMA4D) ELISA Kit |
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abx519948-96tests | Abbexa | 96 tests | EUR 801.6 |
Mouse Semaphorin 6B (SEMA6B) ELISA Kit |
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abx519950-96tests | Abbexa | 96 tests | EUR 801.6 |
Mouse Semaphorin 6C (SEMA6C) ELISA Kit |
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abx519953-96tests | Abbexa | 96 tests | EUR 801.6 |
Mouse Semaphorin 3E (SEMA3E) ELISA Kit |
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DLR-SEMA3E-Mu-48T | DL Develop | 48T | EUR 679.2 |
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Semaphorin 3E (SEMA3E) in samples from serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
Mouse Semaphorin 3E (SEMA3E) ELISA Kit |
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DLR-SEMA3E-Mu-96T | DL Develop | 96T | EUR 889.2 |
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Semaphorin 3E (SEMA3E) in samples from serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
Mouse Semaphorin 7A (SEMA7A) ELISA Kit |
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DLR-SEMA7A-Mu-48T | DL Develop | 48T | EUR 609.6 |
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Semaphorin 7A (SEMA7A) in samples from serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
Mouse Semaphorin 7A (SEMA7A) ELISA Kit |
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DLR-SEMA7A-Mu-96T | DL Develop | 96T | EUR 793.2 |
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Semaphorin 7A (SEMA7A) in samples from serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
Mouse SEMA7A(Semaphorin 7A) ELISA Kit |
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EM1353 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.188 ng/ml |
Mouse Semaphorin 3A(SEMA3A) ELISA kit |
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E03S0355-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3A(SEMA3A) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Semaphorin 3A(SEMA3A) ELISA kit |
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E03S0355-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3A(SEMA3A) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Semaphorin 3A(SEMA3A) ELISA kit |
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E03S0355-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3A(SEMA3A) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Semaphorin 3C(SEMA3C) ELISA kit |
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E03S0356-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3C(SEMA3C) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Semaphorin 3C(SEMA3C) ELISA kit |
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E03S0356-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3C(SEMA3C) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Semaphorin 3C(SEMA3C) ELISA kit |
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E03S0356-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3C(SEMA3C) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Semaphorin 3D(SEMA3D) ELISA kit |
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E03S0357-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3D(SEMA3D) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Semaphorin 3D(SEMA3D) ELISA kit |
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E03S0357-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3D(SEMA3D) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Semaphorin 3D(SEMA3D) ELISA kit |
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E03S0357-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3D(SEMA3D) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Semaphorin 3E(SEMA3E) ELISA kit |
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E03S0358-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3E(SEMA3E) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Semaphorin 3E(SEMA3E) ELISA kit |
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E03S0358-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3E(SEMA3E) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Semaphorin 3E(SEMA3E) ELISA kit |
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E03S0358-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3E(SEMA3E) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Semaphorin- 3G, Sema3g ELISA KIT |
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ELI-07027m | Lifescience Market | 96 Tests | EUR 1038 |
Mouse Semaphorin- 3A, Sema3a ELISA KIT |
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ELI-07269m | Lifescience Market | 96 Tests | EUR 1038 |
Mouse Semaphorin- 3B, Sema3b ELISA KIT |
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ELI-07273m | Lifescience Market | 96 Tests | EUR 1038 |
Mouse Semaphorin- 3C, Sema3c ELISA KIT |
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ELI-07276m | Lifescience Market | 96 Tests | EUR 1038 |
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Two genes, LBH and SHF, confirmed decrease expression ranges in AD circumstances than management topics. That is in step with the gene expression ranges of each the genes in mouse which have been negatively correlated with Aβ accumulation. These outcomes, obtained from the integrative method, counsel that LBH and SHF are related to the AD pathogenesis.
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